Senior Scientist II – ADC Reaction Engineer

Senior Scientist II – ADC Reaction Engineer

• Full-time
• Salary Min: 109500
• Salary Max: 208500
• Workday Global Grade: 18
• Compensation: USD 109,500 - USD 208,500 - yearly

Role Overview

The successful engineering candidate will play a key role in the R&D Process Engineering function. The core deliverable of R&D Process Engineering is to develop robust manufacturing processes and advance innovative technologies using strong engineering fundamentals. Candidates should have a demonstrated capability to model antibody drug conjugate (ADC) kinetics and mechanisms, experience with drug linker and drug substance process design, development of flow chemistry reactor platforms, handling of highly potent compounds, leadership of novel reactor configuration development (photochemistry, electrochemistry, membrane reactors, etc.),

and expertise in computational fluid dynamics to support reactor design and tech transfer. Prior reaction development and scale‑up experience with ADC processes, including reaction and purification, is required.

Key Responsibilities:

• Develop robust manufacturing processes supporting assets through all phases of development.
• Participate in and/or lead project teams for development and characterization of new small and large molecule assets. Establish, communicate, and execute research plans.
• Develop commercial‑ready manufacturing processes in the laboratory and demonstrate the processes in the pilot plant.
• Set project strategies, define project responsibilities and timelines, and provide leadership in a matrixed team setting.
• Address challenging problems with chemical and biochemical reactions, separations, and/or isolations using expertise in reaction kinetics, transport phenomena, and mathematical modeling.
• Develop and apply process analytical technologies and data‑rich experimentation tools to build reaction and process understanding via model‑guided experimentation.
• Build data‑driven and knowledge‑driven models to facilitate successful scale‑up and tech transfer.
• Author and/or review technical documents summarizing process development efforts and contribute to regulatory filings.
• Exhibit a collaborative nature in identifying process challenges on a wide range of projects and communicate findings and recommendations effectively through multidisciplinary interactions.
• Author publications and present at scientific conferences.

Qualifications:

• BS, MS, or PhD in Chemical/Bio Engineering or related field and 12+ (BS), 10+ (MS), or 4+ (PhD) years of relevant industrial experience.
• Strong background in chemical engineering with proven ability to demonstrate skills in this field.
• Demonstrated capability to model antibody drug conjugate kinetics and mechanisms.
• Experience with drug linker and drug substance process design, including tech transfer and scale‑up.
• Development of flow chemistry reactor platforms, including those used for ADCs.
• Experience with highly potent compound handling.
• Leadership of novel reactor configuration development (photochemistry, electrochemistry, membrane reactors, etc.).
• Expertise in computational fluid dynamics to support reactor design and tech transfer.
• Strong team player with effective oral and written communication skills for facilitating collaborations and leading cross‑functional process development teams.

Compensation and Benefits

Salary range: USD 109,500 – USD 208,500 per year. Compensation may vary based on geographic location and other factors. We offer a comprehensive benefits package that includes paid time off (vacation, holidays, sick leave), medical/dental/vision insurance, and a 401(k) plan. Eligible employees may participate in long‑term incentive programs.

Abb Vie is an equal‑opportunity employer. Veterans and individuals with disabilities are encouraged to apply.