Scientist II: Quantitative, Translational & ADME Sciences

Overview

Scientist II:
Quantitative, Translational & ADME Sciences

Quantitative, Translational & ADME Sciences Department (QTAS)

The successful candidate will be responsible for non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples, including extraction, data analysis and interpretation.

Length of Assignment – 6 months

On-Site Position

First Shift, Mon-Fri, 8am – 5pm (possibility of earlier than 8am depending on job tasks)

Level and compensation will be commensurate with experience.

• Perform high throughput quantitative in vivo and in vitro LC-MS/MS analysis, troubleshooting and problem solving of small molecule compounds from various bio-matrices.
• Operate, perform routine maintenance, and hands-on troubleshooting of AB Sciex LC-MS/MS systems.
• Train and mentor junior scientists.
• Maintain excellent documentation of all work including LIMS, electronic notebooks, test methods, and protocols.
• Work closely with multiple teams across Discovery and QTAS to support bioanalysis.
• Write or contribute to study reports for regulatory submissions.

• M.S. (2+ years), or B.S. (6+ years) in analytical chemistry or related field years of relevant academic/pharmaceutical industry experience.
• Proven method development experience using various extraction, chromatographic and analytical methodologies.
• Proven experience with quantitative bioanalysis of small molecules.
• Proven experience operating and troubleshooting Agilent HPLCs, Leap/CTC PAL autosamplers and AB Sciex Mass Spectrometers
• The ideal candidate is detail oriented and committed to generating high-quality results within tight deadlines and across different projects.
• Proven ability to work independently or under minimal supervision in a high-throughput environment to design and conduct experiments, interpret, document, and communicate results, as well as in a team environment to collaborate successfully across other groups within R&D.
• Strong communication, interpersonal, and presentation skills.
• Work experience in regulated bioanalysis and/or CRO Facility settings is a plus.
• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, grasps the "essence" and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.