Scientist

Overview

The successful candidate will be responsible for non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples, including extraction, data analysis and interpretation. This role also involves high throughput quantitative in vivo and in vitro LC-MS/MS analysis, troubleshooting and problem solving of small molecule compounds from various bio-matrices.

• Perform non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples, including extraction, data analysis and interpretation.
• Perform high throughput quantitative in vivo and in vitro LC-MS/MS analysis, troubleshooting and problem solving of small molecule compounds from various bio-matrices.
• Operate, perform routine maintenance, and hands-on troubleshooting of AB Sciex LC-MS/MS systems.
• Train and mentor junior scientists.
• Maintain excellent documentation of all work including LIMS, electronic notebooks, test methods, and protocols.
• Work closely with multiple teams across Discovery and QTAS to support bioanalysis.
• Write or contribute to study reports for regulatory submissions.
• First Shift, Mon-Fri, 8am - 5pm (possibility of earlier than 8am depending on job tasks).

• M.S. (2+ years), or B.S. (6+ years) in analytical chemistry or related field with years of relevant academic/pharmaceutical industry experience.
• Proven method development experience using various extraction, chromatographic and analytical methodologies.
• Proven experience with quantitative bioanalysis of small molecules.
• Proven experience operating and troubleshooting Agilent HPLCs, Leap/CTC PAL autosamplers and AB Sciex Mass Spectrometers.
• Detail oriented and committed to generating high-quality results within tight deadlines and across different projects.
• Proven ability to work independently or under minimal supervision in a high-throughput environment to design and conduct experiments, interpret, document, and communicate results, as well as in a team environment to collaborate successfully across other groups within R&D.
• Strong communication, interpersonal, and presentation skills.
• Work experience in regulated bioanalysis and/or CRO Facility settings is a plus.
• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, grasps the "essence" and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.
• Quantitative LC-MS experience.
• Proven record of independent work.
• Understanding of small molecule analysis in biomatrix.
• Understanding of peptides and proteins in biomatrix is a plus.
• Reverse phase method development is a plus.

• Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through Blue Cross Blue Shield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.
• Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through Met Life. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
• Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
• 401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.
• Technical Certification Bonus: Synectics awards a bonus of up to $500 for an approved professional certification related to your current position. One Certification Bonus per calendar year. Eligible employees receive the bonus 90 days after documentation confirming successful completion is received.
• Equal Opportunity
  
  Employer:
  
  Synectics is an equal opportunity employer.