Talent community Antibody Drug Conjugate Scientists

Company Description

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us at  Follow @abbvie on Linked In, Facebook, Instagram, X and You Tube.

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us at  Follow @abbvie on Linked In, Facebook, Instagram, X and You Tube.

Abb Vie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013, following separation from Abbott. Abb Vie combines the focus and passion of a leading-edge biotech with theexpertiseand capabilities of a long-established pharmaceutical leader, to develop and market advanced therapies that address some of the world's most complex and serious diseases.

Abb Vie employs approximately
50,000 people worldwide and markets medicines in more than 170 countries.

Abb Vie Process Chemistry is responsible forthe chemical development of Abb Vies clinical candidates. We areseekingexperiencedcandidatestoconduct process research and development ofdrug conjugates from pre-clinical through clinical development.

We are looking for a highly motivated person who canmake scientific contributions across synthetic molecule modalities, with a focus on driving the development of drug-conjugateprogramsfrompreclinicaltolate-stage development. Roles and responsibilities will becommensuratewith experience and could range from contributions asanindividualmemberon project teams developing Drug Substance processes to leading cross functional project teamsestablishingCMCprogram strategyforclinical assets.

The candidate will lead in the development of conjugation chemistry as well as downstream unit operations culminating in drug substance. The candidate will serve as the chemistry representative on the Drug Substance team for drug-conjugate development programs and wouldbe responsible for developing timelines and executing activities required for drug substance. Working with analytical and manufacturing colleagues, the candidate will develop productive collaborations and communications with scientific teams.

The role may also have supervisory responsibilities focused on the mentoring and development of direct reports which may be working onaligned or alternate programs.

• The candidate willparticipateonand/orlead activities associated with process development and characterization for newdrugconjugates.
• Develop and characterize drug-conjugate(and other modalities) processes in the laboratory and translate them to scalable processes.
• Participateonand/orleadproject teams toenable CMCdeliverables(materials,methods,milestones).
• Authorand review key regulatory documents, laboratory data, technicalreportsandinternal/external presentations and publications.
• The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, drug product development, and program management. The selected candidate will collaborate withand/orleadcross-functionalCMC teamsto advancepre-clinical and clinical candidates.
• The candidate will understand and adhere to corporate standardsregardingcode of conduct,safetyand GXP compliance.
• The candidate maysuperviseone or moredirectreportsthat may be associated withotherprograms but befullyresponsiblefortheirmentorshipandcareerdevelopment.

• Minimally BS(12+ years); MS (10+ years) or PhD (4+ years) in Chemistryor allied field,with2+ years ofpreviouswork experience in a pharmaceutical laboratory setting.
• Experience indrug-conjugate process developmentisarequirement.
• Proven scientific leadership; strong interpersonal and communication skills forfacilitatingcollaborations and a demonstrated ability to lead cross-functional process development teams.
• The successful candidate will have a strong understanding of modern organic chemistry, mechanistic theory, control…