Scientist, Research Scientist, Data Scientist

Scientist I (LC-MS/MS) – Entry level position

$38 - $41/hr medical benefits available at a cost. 6 month initial contract with possibility of extension. Onsite in North Chicago, IL. Standard laboratory hours 8 am to 5 pm M-F.

Orion Group and our largest US client have an exciting contract opportunity for a Scientist I in North Chicago, IL! This is an early career position and our client is seeking excited Scientists with some experience with the operation of instrumentation used for LC-MS/MS and review and quantitation of LC-MS/MS data.

The Quantitative, Translational, and ADME Sciences Department in North Chicago, IL is seeking a highly motivated team member to operate in an LCMS-based quantitative bioanalytical role to support research and development projects.

The successful candidate will be in a fast-paced, dynamic environment with minimal supervision once trained. The candidate will be responsible for quantitative LC-MS/MS bioanalysis of synthetic molecules and peptides, data analysis and interpretation, and documentation.

• Perform quantitative LC-MS/MS of synthetic molecules and peptides from in‑vitro and in‑vivo biomatrices to support ADME bioassays and PK/PD studies.
• Operate and troubleshoot LC-MS/MS instrumentation and perform routine maintenance of LC-MS/MS equipment.
• Maintain excellent documentation of all work, including electronic lab notebooks, methods, and protocols.
• Measure drug concentrations.
• Spend half of the day working in the lab and the other half reviewing LC-MS/MS data from previous afternoon.

• Bachelor’s degree in a scientific field (e.g., chemistry, biology, pharmacology, or related disciplines), with typically 0-3 years of experience, or a master’s degree with no additional experience.
• Experience with quantitative bioanalysis of synthetic molecules and peptides.
• Hands‑on experience with one or more current LC-MS/MS platforms (e.g., Sciex triple quadrupoles, Agilent HPLCs, Shimadzu HPLCs, PAL autosamplers, ADDA, LS‑II) and software (e.g., Analyst, Discovery Quant, Lead Scape, Sciex OS, Electronic Laboratory Notebook).
• Familiarity with automated sample preparation platforms.
• Familiarity with ADME, PK, PD, and bioassays.
• A good understanding of analytical methodologies used for synthetic molecules and peptide quantitation (acquisition, processing, and troubleshooting).
• Ability to work independently or under minimal supervision to conduct experiments, as well as interpret, document, and communicate results.
• Ability to balance generating high quality data within a standardized, streamlined, and high‑throughput environment.