Senior Scientist , Analytical & Purification Sciences

Job Description

The Analytical and Purification Sciences (APS) group offers an exciting opportunity for a Senior Scientist to join the Technology and Therapeutic Platforms organization within Discovery Research  APS group provides enabling technologies to support Discovery Medicinal Chemistry initiatives. This scientist will execute compound purification using preparative HPLC and/or SFC, devise innovative solutions to complex analytical and separation problems, and serve as a lead scientist on one or more projects, critically evaluating scientific advances and integrating them into research programs.

• Maintain a high level of productivity in the laboratory setting.
• Collaborate with medicinal chemistry teams by developing methods and providing technical guidance to solve analytical and purification problems.
• Innovate within the APS group to develop efficient workflows for sample prioritization and client communication.
• Execute compound purification on milligram to gram scale using preparative HPLC and/or SFC to support small molecule drug discovery projects.
• Maintain analytical and preparative HPLC and SFC instrumentation and independently troubleshoot instrument problems.
• Proactively mentor colleagues in technical development and in establishing positive and productive working relationships.
• May supervise one or more direct reports.
• Keep abreast of current literature and industry trends to assess new approaches in high-throughput purification and analytical technologies, proposing and implementing new initiatives.
• Maintain a highly productive purification workflow, establishing strategies that optimize available equipment and personnel and promote efficiency and enable new paradigms in Medicinal Chemistry.
• Demonstrate a high degree of responsibility in maintaining scientific standards and safe laboratory practices.
• Keep accurate and current records of research and/or project related activities according to Abb Vie policies.

• PhD or MS in Organic Chemistry, Analytical Chemistry, or related fields with 0+ years (PhD); 8+ years (MS) or 10+ years (BS) of postdoctoral and/or pharmaceutical industry experience.
• Hands‑on experience with analytical and preparative scale HPLC and/or SFC.
• Ability to operate and troubleshoot a variety of analytical and preparative instrumentation hardware and software.
• Knowledge of synthetic organic chemistry and the ability to communicate effectively with medicinal chemistry teams.
• Demonstrated record of achievement in chiral/achiral purification on milligram to gram scale for a variety of programs using multiple approaches and technologies.
• Proven effective written and verbal communication skills and ability to interact with scientists and engineers.

• Experience in analytical and purification techniques for peptides.
• Experience working in a fast‑paced purification group and communicating effectively with Medicinal Chemistry teams.
• Experience in reversed‑phase separations using HPLC.
• Experience in chiral separations using HPLC and SFC.
• Experience with instrument development, automation, programming, and data analytics.

• Builds strong relationships with peers and cross‑functionally with partners outside of the team to enable higher performance.
• Learns fast, grasps the essence, and can change course quickly when indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation, and manages reality.

• Compensation range: $110,000–$140,000 base pay (subject to geographic location and other factors). This range may be modified in the future.
• Comprehensive benefits package, including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees.
• Eligibility to participate in short‑term incentive programs.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, and serving our community. Equal Opportunity Employer / Veterans / Disabled.

US & Puerto Rico applicants seeking reasonable accommodation: