Senior Biologics Drug Product Development Scientist

About Abb Vie

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience, and products and services in our Allergan Aesthetics portfolio.

Biologics Drug Product Development (Bio DPD), a part of Development Sciences within Abb Vie’s R&D, is a global organization that is responsible for drug product formulation and process development, and definition of the product presentation for biologics (proteins, conjugates, peptides, neurotoxins, etc.) and genetic medicine (AAV, LNPs, Cell Therapy).

Abb Vie is seeking a highly motivated candidate for the position of Senior Scientist II / Principal Scientist I, located in North Chicago, IL. The role will be an integral part of the product development and CMC teams and will have strong collaborations with stakeholders, including discovery research, analytical research and development, bioprocess development, combination products development, product development science and technology, pilot plants and third‑party manufacturers.

• Represent Bio DPD in the cross‑functional Product Presentation and Device Strategy Team (PPDST) and the CMC Team.
• Effectively and timely communicate development plans, risks, and mitigation plans to stakeholders and line management.
• Support scale‑up and technology transfer activities to internal and external manufacturing sites.
• Lead the design and execution of biologics drug product formulation and process development, characterization and robustness studies.
• Initiate and/or support scientific initiatives to drive innovation, continuously enhance capabilities and platforms, and improve business processes.

• Level is determined based on education and years of experience.
• BS, MS, or PhD in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related disciplines.
• Senior Scientist II: 12+ (Bachelors), 10+ (Masters), or 4+ (PhD) years of relevant industry experience.
• Principal Scientist I: 14+ (Bachelors), 12+ (Masters), or 6+ (PhD) years of relevant industry experience.
• Proven ability to solve critical scientific problems.
• Experience with biologics (proteins, conjugates, peptides and/or neurotoxins), parenteral synthetic molecules and/or genetic medicine (AAV, LNPs, cell therapy) drug product process development.
• Experience with sterile manufacturing unit operations (freeze‑thaw, compounding, mixing, filtration and filling, lyophilization), characterization, scale‑down models, simulation, scale‑up, technology transfer, and batch record authoring.
• Experience leading drug product development as the functional lead within cross‑functional teams.

• Hand‑on experience with authoring regulatory filings for biologics and sterile parenteral products.
• Understanding of relevant cGMP and regulatory guidance for biologics and sterile parenteral products.
• Experience in managing third‑party manufacturers of sterile parenteral products.
• Experience with quality risk management and control strategies for biologics and sterile parenteral products.

• Deep scientific knowledge and significant hands‑on experience with drug product process development and tech transfer.
• Effectively communicates to influence without authority, drives technical excellence, and inspires continuous improvement.
• Builds strong relationships with peers and cross‑functional partners to enable higher performance.
• Connects ideas from disparate fields, integrates data and information quickly, and takes risks to achieve the highest performance.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range.
  
  This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short‑term incentive programs.
• Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico applicants seeking a reasonable accommodation: