Senior Scientist II - Biologics Drug Product Development

Job Description

Abb Vie's Biologics Drug Product Development (Bio DPD) within Development Sciences is a global organization responsible for drug product formulation and process development, and definition of product presentation for biologics (proteins, conjugates, peptides, neurotoxins, etc.) and genetic medicine (AAV, LNPs, Cell Therapy). Abb Vie seeks a highly motivated Senior Scientist II located in North Chicago, IL, with a proven track record in biologics drug product formulation development, predictive stability, in‑use, and quality risk management.

• Lead matrix drug product teams for one or more internal and external projects and represent Bio DPD in the cross‑functional Product Presentation and Device Strategy Team (PPDST) and the CMC Team.
• Lead the design and execution of biologics drug product formulation development, characterization and robustness studies.
• Serve as subject matter expert in biologics predictive stability modeling, in‑use and administration procedures, and QRM.
• Effectively and timely communicate development plans, risks, and mitigation plans to stakeholders and line management.
• Initiate and/or support scientific initiatives to drive innovation, continuously enhance capabilities and platforms, and improve business processes.

• Bachelor’s, Master’s, or PhD in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related disciplines with 12+ years (Bachelors), 10+ years (Masters), or 4+ years (PhD) of relevant industry experience.
• Proven ability to solve critical scientific problems.
• Experience leading drug product development as the functional lead within cross‑functional teams.
• Strong experience with biologics (proteins, conjugates, peptides and/or neurotoxins) and/or genetic medicine (AAV, LNPs, cell therapy) formulation development, and QRM.
• Strong experience in predictive stability modeling (statistical, phenomenological, mechanistic, and/or AI/ML) for biologics.
• Strong experience in in‑use compatibility and stability for biologics products.
• Strong experience in quality risk management.

• Understanding of relevant cGMP and regulatory guidance.
• Experience with sterile manufacturing unit operations (freeze‑thaw, compounding, mixing, filtration and filling) development, characterization, scale‑up and technology transfer.
• Experience managing third‑party manufacturers of sterile parenteral products.
• Experience with quality risk management and drug product control strategies.

• Deep scientific knowledge and significant hands‑on experience with predictive stability modeling, administration procedures and risk management.
• Effectively communicates to influence without authority, drives technical excellence, and inspires continuous improvement.
• Builds strong relationships with peers and cross‑functional partners to enable higher performance.
• Connects ideas from disparate fields, integrates data and information quickly, and takes risks to achieve the highest performance.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and may ultimately pay more or less than the posted range.

This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

This job is eligible to participate in our long‑term incentive programs.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer, Veterans, Disabled.