Senior Scientist II Medicinal Chemistry, Oncology

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, and eye care, as well as products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit

• Conduct research in a large, multi‑functional medicinal chemistry organization.
• As part of a project team, devise and execute synthetic routes to generate potential drug targets.
• Learn to use institutional software and tools to enable and accelerate design of new drug targets.
• Conceive and execute hypothesis‑driven medicinal chemistry projects to optimize safety, ADME, and efficacy.
• Optimize routes to scale‑up materials for key in vivo studies.
• Apply novel synthetic methodologies to access challenging targets.
• Analyze products using NMR, HPLC, LCMS, SFC, and other analytical tools to characterize reaction yields, product purity, and enantiomeric excess.
• Analyze and interpret in vitro and in vivo data from preclinical studies to inform design of next‑generation potential drug targets.
• Create scientific presentations and manuscripts for effective communication with internal stakeholders and the international chemistry community.

Must have a PhD in Organic Chemistry or a related scientific field and two years of academic or industry laboratory research experience. The mandatory experience includes at least two years with each of the following:

• conceiving and executing synthetic organic chemistry projects with knowledge of contemporary synthetic techniques;
• characterizing organic compounds using NMR, HPLC, LCMS, and SFC to quantify reaction yields, product purity, and enantiomeric excess;
• designing and executing multi‑gram syntheses, multi‑step synthesis campaigns, and reaction optimization;
• using electronic lab notebooks;
• acting as a lead scientist in an area of expertise on one or more projects;
• training and mentoring junior scientists.

Alternatively, a MSc in Organic Chemistry or a related scientific field with four years of academic or industry laboratory research experience will be accepted. The required experience includes at least four years with each of the six items listed above. Experience may be gained concurrently, and any suitable combination of training, education, and work experience will be considered.

Salary Range: $ – $ per year.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees. This job is eligible to participate in our short‑term and long‑term incentive programs.

Abb Vie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is Abb Vie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only – to learn more, visit

US & Puerto Rico applicants seeking a reasonable accommodation,  to learn more: