Associate Scientist Solid StateMaterial Science

Company Description

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio.

Abb Vie’s mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience, as well as products and services in our Allergan Aesthetics portfolio.

The Molecular Profiling and Drug Delivery (MPDD) function within the Synthetic Molecules CMC organization is accountable for a broad range of deliverables across various stages of drug discovery and development. During lead optimization and through candidate selection, MPDD scientists utilize state of the art automation and computational tools supported by expertise in biopharmaceutics, drug delivery, and solid‑state chemistry to collaboratively progress candidates with higher probability of success into development and advise clinical formulation strategy.

From candidate selection through clinical proof of concept and product launch, MPDD scientists work in cross‑functional teams to identify the commercial solid form of the active pharmaceutical ingredient (API) and establish structure‑property‑performance correlations to help deliver robust commercial processes and align control strategies across drug substance and product. They also transition drug substance isolation processes and relevant physical characterization methods to commercial manufacturing sites and work within teams to ensure successful regulatory submissions.

Solid State Chemist/Materials Scientist within Abb Vie's MPDD organization work in cross‑functional teams to support projects through all phases of development (Lead Optimization to Process Validation). In early development, they identify solid form of the active pharmaceutical ingredient (API) and develop scalable API isolation processes for early clinical studies. During Phase II, they work with engineers and formulation scientists to establish structure‑property‑performance correlations and deliver commercial API isolation processes with optimized physical properties.

In the final stages of development, they collaboratively transition isolation processes and relevant physical characterization methods into the commercial manufacturing sites. Throughout development, they work with relevant teams to ensure successful regulatory submissions. In order to develop and implement robust solutions, Solid State Chemists/Materials Scientist at Abb Vie use a very diverse set of experimental, analytical and modeling techniques and tools.

Abb Vie’s MPDD organization is seeking a highly motivated, talented, and creative scientist who is passionate in solid‑state and materials characterization for an Associate Scientist I position. This person will support solid‑form development of clinical candidates, drug substance process development, and materials characterization spanning the drug substance and drug product interface.

• Independently execute solid‑state activities, including polymorph screening, salt screening, and materials characterization to support pipeline projects.
• Support API crystallization, isolation, and milling process development to enable timely clinical deliveries with MPDD project leads.
• Demonstrate strong data interpretation and troubleshooting skills by evaluating experiments and instrumentation, and by suggesting, designing, and pursuing relevant experiments.
• Lead and support group safety, lab management, instrument maintenance, and overall laboratory operations to ensure efficient use of time, equipment, supplies, and reagents.
• Learn and effectively implement new experimental techniques and protocols, while applying basic scientific principles and consulting…