Senior Scientist l, QTAS & ADME Sciences

About Abb Vie

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across key therapeutic areas including immunology, oncology, neuroscience, and our Allergan Aesthetics portfolio.

Abb Vie is seeking a highly motivated and experienced scientist to join our Quantitative, Translation & ADME Sciences (QTAS) team in North Chicago. The ideal candidate will have strong expertise with in‑vitro models, drug metabolizing enzyme function, drug‑drug interaction concepts, and quantitative bioanalysis, and the ability to spot, ideate and drive cutting‑edge science. Applicants with experience in adjacent areas such as drug permeability and transport, receptor pharmacology, or pharmacokinetic modeling are desirable.

In this role, you will implement innovative quantitative approaches to advance translational ADME, conduct laboratory work, and contribute to the global in‑vitro ADME strategy. You will qualify, confirm, and evaluate new technologies and support mechanistic and translational understanding of early and late‑stage small molecules to advance drug candidates in our pipeline, with opportunities to contribute to broader areas within DMPK.

• Laboratory experimentation in cellular and subcellular models
• Evaluating novel in‑vitro tools and methods, and applying established methods and concepts to improve prediction of human PK and drug‑drug interaction potential
• As needed, liaise with QTAS, discovery biology/pharmacology to generate data supporting translational, mechanistic models
• Communicate internally and externally on topics related to in‑vitro drug metabolism
• Keep up to date with emerging literature and science in modeling and in‑vitro approaches

• Bachelor’s Degree or equivalent education, typically 10 years of experience;
  Master’s Degree, 8 years;
  PhD, no experience required
• Strong experience in cell culture methods, including hepatocytes and cell lines
• Deep understanding of drug metabolism and ADME principles including enzyme kinetics, IVIVE, and DDI risk assessment
• Strong and relevant publication record
• Highly motivated, self‑driven, results‑oriented with excellent communication and presentation skills; capable of working both individually and as part of a team
• Passion for generating ideas, learning, solving technical problems, and applying new technologies to further scientific goals

• Builds strong relationships with peers and cross‑functional partners to enable higher performance
• Inspires and leads others in areas of expertise
• Learns quickly, grasps the essence, and can change course rapidly when indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others, nurtures innovation, and manages innovation to reality

• Base pay range reflects the range of possible base compensation; the actual compensation may vary by location and other factors
• Comprehensive benefits package, including paid time off (vacation, holidays, sick), medical, dental, and vision insurance, and 401(k) for eligible employees
• Eligibility to participate in short‑term incentive programs

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, and serving our community. Equal Opportunity Employer / Veterans / Disabled.

US & Puerto Rico applicants seeking a reasonable accommodation may visit .