Senior Scientist II, Chemistry; Drug Conjugates

Job Description

We are looking for a highly motivated person who can make scientific contributions across synthetic molecule modalities, with a focus on driving the development of drug‑conjugate programs from FIH to late‑stage development. The candidate will lead in the development of conjugation chemistry as well as downstream unit operations culminating in drug substance and may have supervisory responsibilities.

The candidate will serve as the chemistry representative on the Drug Substance team for drug‑conjugate development programs and would be responsible for developing timelines and executing activities required for drug substance. Working with analytical and manufacturing colleagues, the candidate will develop productive collaborations and communications with scientific teams.

• Lead activities associated with process development and characterization for new drug conjugates.
• Develop and characterize drug‑conjugate (and other modalities) processes in the laboratory and translate them to scalable processes.
• Utilize expertise to generate internal collaborations as necessary to further program goals.
• Author and review key regulatory documents, laboratory data, technical memos and reports.
• Interact multi‑disciplinarily with organic chemists, analytical chemists, engineers, drug product development, and program management; collaborate with cross‑functional CMC teams to advance pre‑clinical and clinical candidates.
• Encourage ideas for continuous improvement activities and initiatives within the work group.
• Understand and adhere to corporate standards regarding code of conduct, safety and GXP compliance.

• Bachelor's degree or equivalent education and typically 12 years of experience, Master’s degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience.
• Experience in drug‑conjugate process development.
• Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross‑functional process development teams.
• Strong understanding of modern organic chemistry, mechanistic theory, control strategy development, and regulatory starting material strategies.

• Learns fast, grasps the essence and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

• Comprehensive package including paid time off, medical/dental/vision insurance, and 401(k) eligibility.
• Eligibility for long‑term incentive programs.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, and serving our community. Equal Opportunity Employer/Veterans/Disabled.