Scientist , Automation

About Abb Vie

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us  Follow @abbvie onLinked

In,Facebook,Instagram,Xand You Tube .

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us  Follow @abbvie onLinked

In,Facebook,Instagram,Xand You Tube .

The Molecular Profiling and Drug Delivery (MPDD) function within the Small Molecule CMC organization is accountable for a broad range of deliverables across various stages of drug discovery and development. During lead optimization and through candidate selection, MPDD scientistsutilizestate of the art automation and computational tools supported byexpertisein biopharmaceutics, drug delivery, and solid-state chemistry to collaboratively progress candidates with higher probability of success into development andadviseclinical formulation strategy.

From candidate selection through clinical proof of concept and product launch, MPDD scientists work in cross functional teams to identify the commercial solid form of the active pharmaceutical ingredient (API) and establish structure-property-performance correlations to help deliver robust commercial processes and align control strategies across drug substance and product. They also transition drug substance isolation processes and relevant physical characterization methods to commercial manufacturing sites and work within teams to ensure successful regulatory submissions.

Abb Vies MPDD organization isseekinga highly motivated,creative, and collaborative scientist withexpertiseinassay development,chemical automation, and integrated workflow design for an Scientist Iposition. The primary role of this position will emphasize analytical chemistry, HPLCmass spectrometry (HPLCMS), laboratory automation, and implement automated and data-enabled workflows that accelerate decision-making and improve throughput in early development sciences.

This individual will contribute to the profiling of physiochemical properties, screening and development of preclinical formulations, and the advancement of platform workflows for emerging modalities of interest.

This role will work closely with cross-functional partners across discovery and development sciences to build andoptimizeintegrated capabilities that support faster,data-driven, more efficient pipeline progression. The successful candidate will have strong hands-on experience inHPLCMS,assay development, automation, and the generation and interpretation of physiochemical data to inform develop ability. Experience with preclinical formulation strategies, workflow optimization, and enabling technologies for novel or complex modalities is highly desirable.

• Scientist Itypicallyrequires Bachelors Degreeor equivalent education with typically 5 years of experience, or Masters Degreeor equivalent education with typically two years of experience in pharmaceutical or related industry.
  
  Preferred educational backgrounds include butarenot restricted to Pharmaceutical Sciences,Pharmaceutical Engineering,Chemical/Biomedical Engineering,Chemistry and Materials Science.
• Familiarity and preferred hands-on experience in physicochemical property assessment related to understanding CMC develop ability profile and potential risk mitigation strategies.
  
  Experimental and automation techniques of interest include butare not limitedto:plate-based optical spectroscopy, liquid handler operation, custom scientific programming and scripting, machine learning and model-building concepts, high-performance liquid chromatography (HPLC), mass spectrometry, powder X-ray diffraction (pXRD), optical microscopy, light scattering techniques, thermal analysis, and other biophysical characterization techniques. Experience with automated data capture,…