Engineer III, Process Development

Position Overview

The Role at Moderna is working to develop first‑in‑class messenger RNA (mRNA) based medicines. We are seeking a highly skilled and motivated individual to join Moderna’s Technical Development organization in Norwood, MA. This role supports the development of manufacturing processes for Moderna’s mRNA‑based medicines to enable clinical and commercial supply, focusing on process understanding, control strategy definition, and transfer of established RNA production processes into fully integrated, automated next‑generation manufacturing systems.

• Serve as a technical SME for RNA manufacturing processes (e.g. IVT, purification) and translate processes into detailed functional and technical requirements for automated systems.
• Participate in the development of process flow diagrams (PFDs), P&IDs, User Requirement Specifications (URS), and Functional Requirement Specifications (FRS) for drug substance manufacturing systems.
• Support the design, scale‑up and implementation of modular and small‑scale process skids in alignment with GxP requirements and Moderna’s global standards.
• Partner with engineering, automation, and equipment vendors to design novel manufacturing platforms that enable closed and continuous operations meeting performance, safety, regulatory and data integrity requirements.
• Contribute to Clean‑In‑Place (CIP) system design and optimization, focusing on process safety, efficiency, and reliability.
• Contribute to technical reviews, design evaluations, and standardization initiatives under Moderna’s Technical Authority governance model.
• Ensure compliance with GxP/GMP regulations and Moderna’s quality and documentation systems.
• Support global site startup activities via tech transfer, process investigations and provide person‑in‑plant support, which may require domestic or international travel (up to 15% of working time).

• BS or MS in chemical engineering, biological engineering, chemistry, biochemistry, or a closely related field.
• BS with 5+ years, or MS with 2+ years of relevant industry experience in bioprocess development, pharmaceutical development or a closely related area.
• Hands‑on experience with chromatography, ultrafiltration, normal flow filtration, and/or development of innovative unit operations or experience in nucleic acid drug development (DNA, RNA, oligonucleotides) and/or nanoparticle delivery.
• Experience in designing, executing, and analyzing scientific experiments.
• Proven ability to support process design and equipment specification in a regulated manufacturing setting.

• Experience in technology transfer and optimization of manufacturing processes.
• Familiarity with bioprocess skid design, automation and process analytical technologies (PAT).
• Experience supporting or leading cross‑functional technical projects.
• Exposure to personalized medicine or individualized manufacturing processes.
• GxP/GMP compliance training and strong understanding of FDA, EMA and ICH regulations.
• Strong communication and collaboration skills across functional teams and organizational levels.
• Demonstrated ability to manage multiple technical priorities within a fast‑paced, matrixed environment.
• Proven problem‑solving and analytical skills to identify and resolve complex technical issues.
• Commitment to data integrity, safety and quality excellence in all work activities.

The salary range for this role is $89,900.00 – $. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. Additional compensation may include an annual discretionary bonus, other incentive compensation or equity award, subject to company plan eligibility criteria and individual performance.

Benefits include:

• Best‑in‑class health care coverage and voluntary benefit programs.
• Access to fitness, mindfulness and mental health support.
• Family planning benefits, including fertility, adoption and surrogacy support.
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days and a discretionary year‑end shutdown.
• Savings and investment opportunities.
• Location‑specific perks and extras.

Moderna is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation should contact the Accommodations team at leavesan