Principal/Lead Separation Scientist; Chemistry
Job in
Nottingham, Nottinghamshire, NG1, England, UK
Listed on 2026-06-20
Listing for:
Sygnature Discovery North America
Full Time
position Listed on 2026-06-20
Job specializations:
-
Science
Research Scientist, Pharmaceutical Science/ Research, Drug Discovery, Biotechnology -
Research/Development
Research Scientist, Pharmaceutical Science/ Research, Drug Discovery, Biotechnology
Job Description & How to Apply Below
About The Role
Principal / Lead Scientist – Separation Science Chemistry (Nottingham, United Kingdom). This full‑time, laboratory‑based position focuses on technical leadership within Separation Science, supporting integrated client projects and specialist analytical and purification services across chemistry, DMPK, formulation and bioscience teams.
Role Responsibilities- Oversee and contribute to the purification lifecycle from crude to pure material.
- Provide subject‑matter expertise across drug discovery programmes, influencing compound progression and workflow decisions for internal and external customers.
- Ensure high‑quality experimental design, execution and reporting across multiple diverse projects.
- Serve as a technical expert for all instrumentation, partner with vendors and train internal team members.
- Represent Separation Science in internal forums and external collaborations.
- Mentor and develop scientists, fostering a high‑performance, collaborative team culture.
- Lead the integration and application of AI and machine‑learning approaches to optimise chromatographic workflows.
- PhD in a Scientific Discipline or master’s degree with experience in Separation Science.
- Proven track record of line management and ability to manage small scientific teams (4–6 people).
- Strong communication skills for explaining complex scientific and technical information to clients and stakeholders at all levels.
- Strong mentoring and coaching skills, with experience in developing junior chromatographers.
- Experience implementing or understanding AI and ML models to improve chromatographic automation.
- Extensive knowledge of state‑of‑the‑art preparative and analytical instrumentation and ability to troubleshoot equipment issues.
- Innovation‑driven mindset, continuously seeking improvements in technology and workflow.
- Desirable: coding ability for chromatographic software and LIMS platforms.
- 25 days annual leave (plus bank holidays).
- Private Medical Insurance.
- Life Insurance.
- Employee Assistance Programme.
- Enhanced Family Friendly Policies.
- Group Pension Scheme.
- 1 paid volunteer day per year.
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