PhD Project "Anti-Tumor Immunity – From Mechanisms to Therapies Translational Medicine

HBIGS Heidelberg Biosciences International Graduate School

Organisation/Company HBIGS Heidelberg Biosciences International Graduate School Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Final date to receive applications 31 Mar 2026 - 23:59 (Europe/Berlin) Country Germany Type of Contract Temporary Job Status Full-time Hours Per Week 40 Offer Starting Date 1 Apr 2026 Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

We have identified a specific immune cell type that effectively suppresses tumor growth in two preclinical models. The aim of this project therefore is to investigate the mechanistic basis of this anti-tumor response in detail and leverage these insights to modulate immune cells to inhibit tumor progression.
Proteomic analyses have revealed several potential mechanistic leads, whose functional roles will be systematically examined. Results will also be expanded using single-cell RNA sequencing to provide a comprehensive view of the immune response against cancer.
The project will combine in vitro studies using primary immune cells and cell lines with exploratory and confirmatory in vivo experiments in mouse models. The project offers a unique opportunity to work at the interface of mechanistic immunology and translational cancer research, to learn state-of-the-art techniques, and to make an independent contribution to the development of innovative therapeutic strategies.

To further advance this project, we seek a highly motivated PhD candidate with a degree in the natural sciences, preferably in biology, immunology, biochemistry or a related field. You will work on a scientifically rigorous, translationally relevant project in a dynamic, collegial environment. We offer close, individualized mentoring that fosters independent and critical thinking. Team spirit, openness, and scientific exchange are core values of our group, and we welcome candidates who are keen to actively contribute their own ideas and shape the project.

The salary is set according to the DFG guidelines for doctoral researchers in biology (65% TVöD).

Languages ENGLISH Level Good

Selection process

Please submit your application exclusively through the HBIGS application system:

We look forward to receiving your application (in electronic form and with at least two references).

Number of offers available 1 Company/Institute Max-Planck Institute for Medical Research Country Germany City Heidelberg Postal Code 69120 Street Im Neuenheimer Feld 305 Geofield