Senior Scientist- Advanced in vitro Systems Research

Location: Dayton

** Worker Type*
* Regular

** Job Description*
* AV has an opportunity for a Senior Scientist within the Health and Performance Technologies Division. This is an onsite position supporting the Air and Space Biosciences division of the 711th Human Performance Wing, located on Wright-Patterson AFB in Dayton OH.  This position will lead and execute  _in vitro_  research programs utilizing microphysiological systems (MPS), new approach methodologies (NAMs), and advanced human-relevant cellular models to improve human health and performance, with a specific application towards Airmen and Guardians.

The ideal candidate will have strong hands-on expertise in mammalian cell culture, experimental execution, and interdisciplinary collaboration within a fast-paced research environment.  They will be responsible for working within the team to perform various assays, such as next-generation sequencing library preparation, microelectrode array, cytokine/inflammatory analysis, and other  _in vitro_  assays. The successful applicant will be experienced in project planning, data analysis and assimilating results into technical reports and presentations.

The successful candidate will be an independent self-starter, have excellent organizational and time management skills, demonstrable written and oral communication skills, and thrive in a collaborative, team-based environment.

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* Key responsibilities include:

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* + Lead, execute, and analyze  _in vitro_  experiments involving MPS and NAM-based platforms. Specific experience with brain models (iPSC-derived brain cells, BBB, microelectrode array) is highly preferred.

+ Characterize and assess various MPS using  _in vitro_  assays to measure neuronal function, cell viability, barrier function, and metabolic activity, as well as other cellular functions.

+ Maintenance, expansion, and experimental manipulation of mammalian tissue culture systems (e.g., iPSCs, primary cells, immortalized cell lines, organoids) using aseptic techniques.

+ Generate high-quality, reproducible datasets and maintain detailed experimental documentation.

+ Contribute to experimental design, protocol development, technical reports, presentations, and scientific publications.

+ Coordinate and collaborate with internal teams, external collaborators, and government scientists to ensure timely delivery of research products.

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* Qualifications:

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* + Ph.D. in a biological discipline, such as Biology, Molecular Biology, Biochemistry, Molecular Genetics, Microbiology, or Immunology. 3+ years of experience in the MPS field is highly desired.

+ A strong background in  _in vitro_  systems, with hands-on experience in mammalian cellular and microbial culture, and advanced laboratory techniques (flow cytometry, microscopy, etc.). Previous experience with MPS/Organ-on-chip and stem cells/iPSCs is highly desired.

+ Data analysis skills, with proven ability to process and interpret complex data. Biostatistics experience is desired.

+ The ideal candidate will possess strong organizational skills and meticulous attention to detail, with the ability to manage multiple projects and deadlines in a fast-paced team-based environment.

** ITAR Requirement:*
* _This position requires access to information that is subject to compliance with the International Traffic Arms Regulations ("ITAR") and/or the Export Administration Regulations ("EAR"). In order to comply with the requirements of the ITAR and/or the EAR, applicants will be asked to provide specific documentation to verify U.S. person status under the ITAR and the EAR.  A "U.S. person" according to their definition is a U.S. citizen, U.S. lawful permanent resident (green card holder), or protected individual such as a refugee, or asylee.

See 22 CFR § 120.15._   _Some positions will require current U.S. Citizenship due to contract requirements._

** Benefits** :  AV offers an excellent benefits package including medical, dental vision, 401K with company matching, a 9/80 work schedule and a paid holiday shutdown.  For more information about our company benefit offerings please visit:
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