Sr. Commercial Data Operations Manager

As the Sr. Commercial Data Operations Manager at Bio Cryst, you will own and optimize the data operations ecosystem across our product portfolio for rare diseases, ensuring reliable data operations and managing sensitive‑data risks.

• Manage and execute data operations between Bio Cryst systems and downstream partners, including commercial, medical affairs, and clinical operations.
• Oversee risk management and data operations for key systems (data transmissions, analytical tools, CRMs, marketing platforms, material review systems).
• Act as an internal advisor on data operations and integrations used across the organization (Patient Services, Sales, Medical, Clinical, IT).
• Establish and maintain a data and risk documentation repository for internal and external data sources, integrations and warehouses.
• Manage Expert Determinations in partnership with Advanced Analytics.
• Support data operations for implementation of system platforms managed by Strategic Data, Insights, and Operations, ensuring integration documentation, risk assessment, business rule alignment, and ongoing optimizations.
• Coordinate and manage data flows between internal sources and external vendors.
• Collaborate with Commercial to size field force territories, create customer target lists, and manage rosters; partner with Commercial Enablement for implementation.
• Collaborate with Medical to size MSL geographies, coverage maps, create KOL lists, and manage rosters; partner with Commercial Enablement for implementation.
• Own commercial data ingestion monitoring and documentation processes for inbound and outbound feeds globally; ensure compliance with US, Japanese, Canadian data privacy and security regulations.
• Partner with the Data Architect to establish and manage predictable data operating models for inbound and outbound transfers.
• Partner with Commercial Enablement to align data flows to high‑impact tools, improving execution and insights.
• Partner with Data Architect to assess, document, and integrate AI/ML tools for Commercial Enablement.

• Bachelor’s degree required; MBA or other advanced degree preferred.
• 6+ years of relevant commercial experience in biotech/pharma; 6+ years preferred or equivalent combination of education and experience.
• Proven ability to operate in a fast‑paced, high‑growth environment.
• Strong understanding of biopharma commercial data operations and sales data analytics infrastructure.
• Creative thinker, self‑directed, able to develop plans, gain alignment, and execute.
• Highly collaborative, flexible, working easily across functions; comfortable engaging all aspects of a commercial business and recommending optimizations.
• Strong customer and partner relationship skills.
• Analytical mindset; uses data to drive strategic decision‑making.
• Strong ability to drive execution through an organization.
• Understanding of cloud systems, master data management, and data warehouses.
• Relevant experience with specialty pharma data preferred; rare disease states preferred.

This role is eligible for remote work in Eastern or Central time zones.

Bio Cryst is an equal opportunity employer and is committed to providing equal employment opportunities without regard to age, race, religion, sex, sexual orientation, gender identity, national origin, veterans status, disability and/or other protected class characteristics. Bio Cryst is committed to complying with all federal, state and local law.