Principal Product Designer Remote

At Twin Health, we empower people to improve and prevent chronic metabolic diseases, like type 2 diabetes and obesity, with a new standard of care. Twin Health is the only company applying AI Digital Twin technology exclusively toward metabolic health.

We start by building a dynamic model of each person’s metabolism — drawing on thousands of data points from CGMs, smartwatches, and meal logs — that maps their personal path to better health. Guided by a dedicated clinical care team, our members have lowered their A1C below the diabetes range, achieved lasting weight loss, and reduced or even eliminated medications, all while living healthier, happier lives.

Working here

Our team at Twin Health is passionate, talented, and united by a shared purpose: to improve the metabolic health and happiness of our members. We believe in empowering every Twin to make a meaningful impact for our members, our clients, and each other, while enjoying a supportive, collaborative work environment.

Twin has been recognized not only for our innovation but also for our culture, including:
Innovator of the Year by the Employer Health Innovation Roundtable (EHIR), selected to CB Insights’ Digital Health 150, and named one of Newsweek’s Top Most Loved Workplace® .

With more than $100 million raised in recent funding, including a $53 million Series E round in 2025 led by Maj Invest, and a $50 million investment in 2023 led by Temasek, Twin is scaling rapidly across the U.S. and globally. Backed by leading venture firms like ICONIQ Growth, Sequoia, Sofina, Temasek, and Peak XV, we are building the most impactful digital health company in the world.

Join us as we reinvent the standard of care in metabolic health.

As a Principal Product Designer, you'll own the end-to-end experience strategy for our mobile app — the primary touchpoint where members manage their health every day. But more than that, you'll be doing something very few designers get to do: inventing the interaction language for agentic AI in healthcare from scratch.

There is no established playbook here. Agentic experiences — where AI acts autonomously on a user's behalf, surfaces proactive guidance, and adapts in real time to behavior and health data — are among the least explored frontiers in product design today. You'll be the person who figures out what these patterns look, feel, and behave like for people managing chronic conditions.

That requires genuine originality, comfort with ambiguity, and the creative confidence to propose something that has never existed before.

This is the highest craft and leadership bar we hire to. You'll be a recognized thought leader internally — setting the quality standard others aspire to, shaping product roadmaps beyond your immediate scope, and leaving a design legacy that outlasts any single feature.

This isn't iteration work. It's an invention.

• Identify and drive mission-critical design initiatives with significant scope and long-term timelines — projects that directly shape the trajectory of the business, not just the product.
• Pioneer agentic UX from 0 to 1 — design entirely new interaction patterns for AI systems that act proactively, make recommendations, and operate with increasing autonomy on behalf of users. You'll be defining conventions that don't yet exist, not referencing ones that do.
• Assist stakeholders across teams in shaping their product roadmaps, bringing a design-led perspective to decisions that extend well beyond your own areas of ownership.
• Lead design strategy across interconnected member journeys — from onboarding through long-term behavior change — defining what "great" looks like, aligning cross-functional partners around it, and seeing it through to shipped product.

• Invent in uncharted territory — bring a high degree of creative originality to problems with no obvious solution. Concept, prototype, and validate novel design patterns that balance AI agency with user trust, transparency, and control.
• Lead high‑complexity initiatives end to end while also serving as a design consultant across smaller‑scale efforts, applying your breadth of experience to raise…