VP Clinical Development & Global Program Lead, Lung Cancer San Diego, CA; South San Francisco, CA; remote

Erascais a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer’s most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer.

Reporting to the Chief Medical Officer , theVPClinical Development and Global Program Lead (GPL) for Lung Cancer will provide medical leadership and oversight ofthelung cancerdevelopmentprogramand collaborate with the CMOacross the Erascaportfolio. Responsibilities will include clinical development strategy,protocol development, registrationalstrategyand execution, KOL and academic site interactions, competitive landscape diligence, presentation of data, andother clinical  addition, the VP will be ahands–on drug developer andwillserve as clinical lead and/or medical monitor onindividualstudies.

Essential Duties and Responsibilities:

• Provide medical direction and high-quality scientific and clinical knowledge to guide the strategy and execution ofthelung cancerprogramandcontribute to clinical decision making across the Erascaportfolio.
  
  Participate inbuildingandmaintaininga culture of rigorous data-driven decision making.
• Lead the clinical developmentsubteamfor all studies in lung cancers.
• Design and implement novel and efficient clinical trialstoassessappropriate endpoints.
• Responsible for leading clinical studysubteams,monitoring overall study integrity, and review, interpretation,and communication of safety and efficacy data.
• Provide overall strategy for clinical aspects of registrational strategies, interactions, and filings. Contribute to global regulatory filings and health authority interactions, including authoring clinical sections for INDs,NDAsand other related documents.
• Serve as Medical lead on clinical program sand r epresent Clinical Development on program teams.
• Partner with Drug Safety to assess the safety profile of compounds.
• Writeor partner in the authoring ofmedical aspects of core study and regulatory documents including clinical research plans, protocols, investigator brochures, clinical studyreportsand regulatory submissions.
• Contribute to the development and review of scientific publications; author manuscripts and collaborate with cross-functional colleagues and thought leaders to meet publication plan objectives.
• Present at scientific, medical,and regulatory meetings.
• Maintaina high levelof clinical and scientificexpertiseby reviewing literature, attending medicalorscientific meetings,and through personalexchangewiththought leaders, investigators,and internal stakeholders and partners.
• Participate in due diligence or other business development activities.
• Hire, develop, and mentor a high functioning team of medical directors and clinical scientists.
• Establish, develop,andmaintainrelationships across
  
  Erasca, particularly with partners and stakeholders in Research and Development.
• Perform all duties in keeping with the Company’s core values,policies and all applicable regulations.

Required

Education and Experience:

• M.D.degreeor equivalent, with subspecialtyfellowshiptraining and board certification or eligibility in Oncology or Oncology/Hematology required.
  
  Additional training and clinical practiceexperiencein thoracic oncology preferred.
• 8-10+ years ofoncologyclinical trial anddrug development experience,including extensive experience in the pharmaceutical or biotechnology industry.
  
  The ideal candidate will bringa combination of clinical practice,…