Senior Manager, Pharmacovigilance, Remote

Remote, US

Pulmovant is a Roivant-backed clinical-stage biotechnology company committed to transforming the lives of patients with pulmonary diseases. Pulmovant’s first investigational candidate, mosliciguat, is designed to provide a novel, once-daily, inhaled treatment option for patients with pulmonary hypertension associated with interstitial lung disease (PH-ILD). Mosliciguat is a potential first-in-class soluble guanylate cyclase activator with a differentiated mechanism of action currently being evaluated in the Phase 3 PHrontier global clinical trial in PH-ILD, but with potential broad applicability across the PH and ILD disease landscape.

Pulmovant recently announced positive results from its Phase 2 PHocus study evaluating mosliciguat for the treatment of pulmonary hypertension associated with interstitial lung disease (PH-ILD), a progressive and life-threatening condition with significant unmet medical needs for patients. PHocus met both primary and secondary endpoints including the highest ever reported pulmonary vascular resistance (PVR) reduction in any randomized controlled PH trial. The robust results, in conjunction with mosliciguat’s once-daily, inhaled administration and potential first-in-class sGC activator profile, strongly position it as a potential single agent treatment and combination therapy for patients with PH-ILD.These

data represent a significant advancement in a devastating disease that affects ~200,000 patients with no or very limited treatment options. A Phase 3 trial is currently underway.

More details can be found in the press release here .

Roivant (Nasdaq: ROIV) is a commercial-stage biopharmaceutical company that aims to improve the lives of patients by accelerating the development and commercialization of medicines that matter. Roivant’s pipeline includes LISRAYA™ (brepocitinib), a potent small molecule inhibitor of JAK1 and TYK2 FDA-approved for the treatment of dermatomyositis in adult patients and also in late-stage development for the treatment of non-infectious uveitis, cutaneous sarcoidosis and lichen planopilaris;

IMVT-1402, a fully human monoclonal antibody targeting FcRn in development across several IgG-mediated autoimmune indications; and mosliciguat, an inhaled sGC activator in development for pulmonary hypertension associated with interstitial lung disease. We advance our pipeline by creating nimble subsidiaries or “Vants” to develop and commercialize our medicines and technologies. For more information, visit  .

The Senior Manager, Pharmacovigilance, will support the ongoing safety surveillance and risk management activities for our pipeline of respiratory therapeutics. In this role, you will oversee case processing, signal detection, and aggregate safety reporting (DSURs) while ensuring compliance with global pharmacovigilance regulations and ICH guidelines. You will serve as a key safety partner to clinical development, regulatory affairs, and medical teams, contributing to risk management plans, safety data review committees, and health authority interactions.

Reporting to the Director, Pharmacovigilance, the ideal candidate brings deep expertise in drug safety operations, hands‑on experience with Argus Safety, and a proven track record managing PV vendors and CRO relationships, along with strong analytical and leadership skills to operate effectively in a fast‑paced, growing biotech environment.

• Serve as a pharmacovigilance subject matter expert supporting Pulmovant's multiple ongoing and future clinical trials, including fast paced Phase 1 studies, and the Phase 3 PHrontier study of mosliciguat in PH-ILD.
• Oversee end-to-end case management for serious adverse events (SAEs), ensuring accurate…