Assistant Director, Compliance Operations, Monitoring Lead

Role Summary

The Assistant Director, Compliance Operations, Monitoring Lead reports to the Head of Compliance Operations and is responsible for the management and execution of Ionis’ risk-based healthcare compliance monitoring program. The role independently assesses adherence to Ionis’ healthcare compliance standards and leverages data analytics to deliver actionable compliance risk insights. This role is flexible for remote candidates in the U.S., with preference given to individuals located in or near the Boston, MA area to enable periodic on-site collaboration.

• Develop and maintain the annual risk-based monitoring plan, including collaboration with third-party consultants to support execution and continuous program improvement
• Lead and execute live (in-person and virtual) and transactional/desktop monitoring in partnership with other compliance team members and third-party consultants
• Define, track, and report key performance indicators (KPIs) and key risk indicators (KRIs) to assess compliance risk trends and monitoring program effectiveness
• Analyze monitoring data to identify trends, outliers, and emerging risk signals that inform monitoring priorities
• Oversee remediation and corrective action plans, including tracking progress and ensuring timely and effective resolution of monitoring findings
• Develop and maintain monitoring dashboards and reports (e.g., Excel, Tableau, Power BI, monitoring system)
• Translate analytics and monitoring results into clear, executive-ready insights
• Support monitoring system implementation and ongoing enhancement efforts
• Partner cross-functionally with Commercial, Medical, Finance, IT, HR, and other stakeholders to align compliance activities
• Provide compliance operational guidance and support for additional compliance initiatives, as needed

• Bachelor’s degree required; advanced degree or relevant certification preferred
• At least 8 years of experience in healthcare compliance monitoring or operations within the pharmaceutical, biotechnology, or life sciences industry, or 6 years with an advanced degree or relevant certification
• Demonstrated knowledge of pharmaceutical compliance laws, regulations, and industry guidance (e.g., OIG, PhRMA, anti-kickback, anti-bribery)
• Recent, hands-on experience with live field and transactional compliance monitoring
• Advanced proficiency in Excel; experience with data visualization and dashboarding tools (e.g., Tableau, Power BI)
• Demonstrated ability to analyze large datasets to identify trends, outliers, and compliance risks
• Experience with compliance monitoring systems, including automated/AI-enabled monitoring tools, preferred
• Proven ability to manage complex projects and external vendors effectively
• Ability to operate independently and collaboratively in a fast-paced, matrixed environment, while exercising sound judgment
• Effective verbal and written communication skills with the ability to convey complex information to diverse audiences
• Demonstrated initiative, adaptability, and willingness to take on new responsibilities as business needs evolve
• High degree of integrity and discretion in handling proprietary and confidential information
• Occasional domestic travel (up to 20%)