Director, US Value & Access

Director, US Value & Access

Headquartered in Carlsbad, California, with offices in Boston and Dublin, Ionis has been pioneering RNA‑targeted medicines for over thirty years. The company is focused on neurology, cardiology and high‑need areas, advancing new approaches in gene editing to provide greater value to patients.

We foster a challenging, motivating and rewarding environment that cultivates innovation and scientific excellence. We invest in hybrid and remote work environments that support enduring relationships and cultural growth.

The Director, Value & Access leads the development and execution of comprehensive value and market access strategies to ensure optimal patient access and commercial success across the designated therapeutic area. This role integrates cross‑functional leadership and collaboration across Commercial, Medical, HEOR, and Regulatory to shape payer strategy, evidence generation, and value communication throughout the product lifecycle.

• Develop and lead U.S. market access strategies aligned with brand and portfolio objectives across a 3+ year horizon.
• Define value proposition and access roadmap from pre‑launch through lifecycle management.
• Shape and implement integrated evidence plans, in partnership with HEOR and Medical Affairs to support access and payer negotiations.
• Serve as the enterprise subject matter expert on access, payer dynamics, and policy trends across the landscape and within specialty and rare disease.
• Oversee development of AMCP dossiers, payer communication tools, and field access tools.
• Guide economic modeling and budget impact analyses to support payer discussions.
• Collaborate closely with Commercial to align access strategy with brand strategy.
• Engage with Government Affairs on policy implications and advocacy priorities.
• Represent the organization in external advisory boards and industry forums.
• Monitor payer landscape, competitive dynamics, and regulatory changes to inform strategy.
• Lead, coach, and develop high‑performing Market Access professionals.
• Select and retain agency partners, holding full budget authority for access strategies.
• Drive cross‑functional alignment in matrixed environments.

• Bachelor’s degree required; advanced degree preferred.
• 15+ years of experience with a Bachelor’s degree (or 10+ with advanced degree) in U.S. Market Access, Value & Access, Payer Marketing, or related roles.
• Proven experience leading access strategy for product launches with a strong understanding of U.S. payer systems and reimbursement pathways.
• Experience with specialty pharmaceuticals and/or rare disease preferred.
• Demonstrated collaboration and leadership experience in matrixed organizations.

Ionis offers an excellent benefits package.

The pay scale for this position is $220,000 to $260,000.

To apply for this position, reference requisition # IONIS
004058.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

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