Senior Clinical Laboratory Scientist (Tues - Sat 6am - 4:30pm

Company Description

Company Description Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real‑world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early‑stage cancer, and treatment selection for patients with advanced cancer.

For more information, visit  and follow the company on Linked In, X (Twitter) and Facebook.

As a Senior Clinical Laboratory Scientist, you are responsible for performing high complexity laboratory testing (next generation sequencing) on patient specimens, performing quality control and quality assurance procedures, and reporting patient results. You’ll comply with all applicable local, state and federal laboratory requirements and operate under the direction of the Laboratory Director and Laboratory Supervisors. This role requires meticulous and organized records, excellent attention to detail, and the ability to multi‑task and be flexible with tasks and schedules.

Must be available to work onsite Saturday - Tuesday from 6am - 4:30pm (AM Shift 4x10 Schedule).

• Accurately perform molecular testing, using a variety of molecular biological techniques including next generation sequencing
• Conduct daily quantitation and qualification assessment of molecular data generated during testing
• Carry out QC/QA activities as part of the Quality program and commitment to patient safety
• Participate in a variety of other essential laboratory activities, including reagent qualification, inventory management, procedure writing, inspection preparation, assay validation and investigation
• Perform and document routine preventive maintenance and independently identify and troubleshoot highly complex problems that adversely affect test performance
• Identify root cause and document all corrective actions taken when test systems Assist with training of new laboratory personnel
• Participate in introduction of assay improvements, new assay configurations and validation
• At times, this position may fill the role of the general supervisor if the general supervisor is off‑site

• Current California Clinical Laboratory Scientist (CLS) or Clinical Genetic and Molecular Biology Scientist (CGMBS) license
• Bachelor of Science in Biomedical Laboratory Science, Clinical Science or related field
• 4-6 years of experience in a CLIA certified laboratory
• Working knowledge of local, state, and federal laboratory regulations
• Experience in molecular testing, nucleic acid extraction, PCR, and sequencing (next generation sequencing)
• Working knowledge of laboratory functions (laboratory regulations, LIMS, Quality, etc.)
• AI & Digital Fluency Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI‑enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.

This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in‑person/ontarget collaboration and work‑from‑home days for individual‑focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in‑office days allows our teams to do the best work and creates the focused thinking time our innovative work requires.

At Guardant, our work model has created flexibility for better work‑life balance while keeping teams connected to advance our science for our patients.

The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or…