SVP, Medical Affairs

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life‑threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR‑T), T-cell receptor (TCR‑T), natural killer (NK) cell‑based therapies, and other emerging platforms designed to transform the treatment of serious diseases.

From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting‑edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta‑cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

Legend Biotech is seeking a SVP of Medical Affairs as part of the Medical Affairs team based in Bridgewater, NJ.

Legend Biotech is seeking a Senior Vice President, Medical Affairs to provide enterprise leadership for the Company's global Medical Affairs organization.

The Senior Vice President, Medical Affairs is a critical enterprise leadership role with significant impact on the scientific, clinical and external medical strategy for Legend’s approved BCMA CAR‑T in multiple myeloma, as well the development of future pipeline programs. This leader will set the overall Medical Affairs vision and strategy, partner closely with collaboration partners, such as Johnson & Johnson, as well as internal cross‑functional leaders, and ensure Medical Affairs is positioned as a strategic driver of clinical understanding, external engagement, lifecycle planning, data generation, and future growth.

This role will provide senior leadership across home office and field‑based Medical Affairs teams and will be accountable for building the capabilities, structure, and talent needed to support CARVYKTI today and Legend’s expanding pipeline, including future in vivo and emerging therapeutic areas. The SVP, Medical Affairs will report to the President, Carvykti Business Unit, will be a member of Carvykti LT and will be based in Bridgewater, NJ.

• Define and execute the Medical Affairs vision, strategy, and operating model across CARVYKTI and the broader pipeline.
• Provide enterprise leadership for lifecycle management, evidence generation, scientific communications, medical launch excellence, and external medical engagement.
• Partner with R&D, Commercial, Regulatory, Safety, Market Access, and Clinical Development to shape product strategy and maximize portfolio value.
• Ensure medical insights and scientific expertise influence key business and development decisions.
• Serve as the senior scientific leader and external ambassador for Medical Affairs.
• Build and maintain relationships with key opinion leaders (KOLs), academic institutions, professional societies, patient advocacy groups, and healthcare stakeholders.
• Lead the global evidence‑generation, publication, and scientific communication strategy.
• Promote scientific excellence, patient‑centered innovation, compliance, and thought leadership across the organization.
• Build and lead a high‑performing Medical Affairs organization capable of supporting current and future business needs.
• Develop organizational capabilities across Medical Strategy, Field Medical, Medical Communications, Evidence Generation, Medical Operations, and Medical Excellence.
• Establish talent, succession, leadership development,…