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Lead Statistical Programmer - Global Studies; Remote

Remote / Online - Candidates ideally in
Fairfield, Fairfield County, Connecticut, 06828, USA
Listing for: Penfield Search Partners Ltd
Remote/Work from Home position
Listed on 2026-05-10
Job specializations:
  • IT/Tech
    Data Scientist, Data Analyst
Salary/Wage Range or Industry Benchmark: 90000 - 120000 USD Yearly USD 90000.00 120000.00 YEAR
Job Description & How to Apply Below
Position: Lead Statistical Programmer - Global Studies (Remote)

Contact:
Neisha Camacho/Terra Parsons -  No 3rd party candidates

We are seeking a highly experienced Statistical Programmer to lead programming activities across global clinical studies. This role operates beyond executional programming, with responsibility for oversight of CRO deliverables, validation of outputs, and end-to-end accountability for statistical programming packages.

Key Responsibilities
  • Lead statistical programming activities across global studies (EU and China exposure preferred)
  • Serve as primary programming lead in collaboration with Biostatistics
  • Develop, review, and validate SDTM and ADaM datasets in accordance with CDISC standards
  • Review specifications and proactively challenge inconsistencies in protocols, SAPs, and dataset definitions
  • Validate program outputs and ensure accuracy, quality, and regulatory compliance
  • Provide oversight and guidance to CRO partners, consolidating and communicating feedback effectively
  • Manage timelines, delivery packages, and milestone commitments
  • Contribute to continuous improvement of programming processes and standards
Core Requirements
  • Strong expertise in CDISC standards, including ADaM and SDTM
  • Demonstrated experience reviewing specs and ensuring high-quality, submission-ready deliverables
  • Working experience in LSAF environment
  • Experience validating CRO programming deliverables
  • Ability to operate with increased performance accountability and ownership

    Strong CRO-facing communication and collaboration skills
  • Proven ability to manage multiple global studies simultaneously
Qualifications
  • Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, or related field
  • 5+ years of SAS programming experience within pharmaceutical/biotech
  • Strong understanding of statistical methods used in clinical trial analysis
  • Knowledge of Good Programming Practices and GCP
Preferred
  • Experience with R programming
Additional Requirements
  • Hands-on experience withLSAF
    - Life Sciences Analytical Framework
  • Practical experience with multiple imputation (MI), particularly under Missing at Random (MAR) assumptions
  • Familiarity with the estimands framework (ICH E9 R1) and managing intercurrent events (ICEs) within ADaM domains using various strategies
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