Director​/Senior Director, IT Operations & Enterprise Services

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been submitted to the U.S. FDA;

IM-1021, a clinical-stage ROR1 ADC; IM-3050, an IND-cleared FAP-targeted radiotherapy; and IM-1617, an IND-cleared solid tumor ADC. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

The Director / Senior Director, IT Operations & Enterprise Services will lead the function responsible for reliable day-to-day technology operations, infrastructure, enterprise services, end-user support, service management, and IT project delivery coordination across Immunome. This leader will ensure employees have the tools, access, support, and technology environment needed to work effectively across office, lab, remote, and future field-based settings.

This role also oversees the IT PMO function for material IT projects and cross-functional technology initiatives, including intake, roadmap visibility, delivery coordination, reporting, and project management discipline. The leader will partner closely with business stakeholders, cybersecurity, compliance, business applications, data architecture, facilities, lab operations, and external service providers to deliver IT services and projects with reliability, transparency, and accountability.

• Lead IT operations, enterprise services, end-user support, infrastructure operations, and day-to-day technology service delivery.
• Maintain a scalable support model across headquarters, additional office locations, lab environments, remote workers, and future field-based roles.
• Own service management processes and Service Now / ITSM capabilities, including intake, routing, prioritization, escalation, metrics, reporting, knowledge management, and continuous improvement.
• Improve the employee technology experience across onboarding, offboarding, access provisioning, device readiness, collaboration tools, enterprise services, and recurring support needs.

• Oversee physical and cloud infrastructure operations, including networks, connectivity, servers, storage, cloud services, backup/recovery coordination, and core enterprise platforms.
• Support technology needs for office spaces, meeting rooms, lab environments, shared work spaces, and other facility-connected technology in partnership with Facilities, Lab Operations, vendors, and business stakeholders.
• Enable multi-location and distributed workforce support through reliable connectivity, device management, secure access, collaboration tools, onboarding processes, and responsive support models.
• Oversee endpoint and device management, asset lifecycle planning, and collaboration/productivity platforms such as Microsoft 365, Teams, SharePoint, Zoom, Box, Adobe, and related enterprise services.

• Lead the IT PMO function for material IT projects and cross-functional technology initiatives.
• Establish practical processes for project intake, evaluation, prioritization support, planning, status reporting, risk/issue management, decision tracking, and escalation.
• Improve visibility into the IT project pipeline, roadmap, dependencies, resource needs, and delivery status.
• Coordinate project execution across IT, business stakeholders, vendors, and cross-functional governance forums to support clear ownership, communication, and follow-through.

• Manage external IT service providers, managed services partners, consultants, project resources, and technology vendors supporting operations, enterprise services, and project delivery.
• Partner with cybersecurity and compliance teams to ensure operational processes support security, access control, audit readiness, business continuity, disaster recovery, and applicable regulated-system requirements.
• Develop and manage budgets for IT operations, infrastructure, enterprise services, endpoint lifecycle, service management, PMO-related tooling, vendors, and licensing.
• Maintain policies, procedures, runbooks, service documentation, project documentation practices, and knowledge management to support consistent execution and audit readiness.

• Build, lead, and develop internal employees, consultants, managed service providers, project managers, and specialized vendors supporting IT operations, enterprise services, and PMO activities.
• Set clear expectations and accountability through metrics, service targets, escalation paths, project reporting,…