Associate Director​/Director, IT

Associate Director / Director, IT

Korsana Biosciences, Inc. – Waltham, Massachusetts, United States

Korsana Biosciences is a private biopharmaceutical company advancing a pipeline of potential best‑in‑class therapies for neurodegenerative diseases. In partnership with Paragon Therapeutics, we have developed Therapeutic Targeting (THETA™), a novel blood‑brain‑barrier‑penetrant shuttle platform designed to enable dramatically higher drug concentration inside the brain and overcome the limitations of earlier shuttle technologies. Our lead program is KRSA‑028, an investigational, shuttled antibody targeting amyloid beta designed to be a best‑in‑class treatment for Alzheimer’s disease.

Our mission is to advance precision‑engineered therapies, designed to address some of the biggest unmet needs in medicine.

The Associate Director / Director of Information Technology is responsible for the day‑to‑day operation, administration, and continuous improvement of the organization's IT infrastructure, information security controls, enterprise applications, and end‑user computing environment. The role serves as the primary technical lead for IT operations, combining hands‑on technical execution with leadership of external service providers and contribution to strategic initiatives. The successful candidate will manage infrastructure, security operations, systems administration, troubleshooting, and project delivery through a combination of direct individual contribution and effective delegation to, and oversight of, the organization’s IT Managed Services Provider (MSP).

This is a highly visible role that requires someone who is comfortable rolling up their sleeves to solve technical challenges while also partnering with senior management on strategy, governance initiatives, and key business projects.

• Serve as the primary owner of day‑to‑day IT operations across in‑office and remote work environments.
• Perform hands‑on administration of Microsoft 365, Entra  (Azure AD), endpoint management platforms, collaboration tools, cloud services, and other enterprise applications.
• Manage and support physical and wireless network infrastructure, VPNs, firewalls, storage systems, and cloud‑based resources.
• Configure, deploy, maintain, and troubleshoot endpoints, software, and business‑critical systems.
• Monitor system performance, availability, capacity, and security, proactively addressing issues before they impact operations.
• Manage backup, disaster recovery, and business continuity solutions.
• Lead technical implementation efforts for new systems, infrastructure upgrades, and technology rollouts.
• Maintain hardware, software, licensing, and IT asset inventories.

• Act as the primary point of contact for the Managed Services Provider (MSP), directing priorities, reviewing performance, and ensuring timely issue resolution.
• Determine which activities are retained internally versus outsourced to service providers.
• Escalate and resolve complex technical issues that require direct internal involvement.
• Partner with vendors on deployments, upgrades, migrations, and troubleshooting activities.
• Participate directly in system implementations and infrastructure projects alongside external partners.

• Maintain and continuously improve the organization's cybersecurity posture through hands‑on administration of security technologies and processes.
• Administer security platforms including endpoint protection, email security, vulnerability management, identity security, and monitoring tools.
• Conduct periodic reviews of user access, security controls, and system configurations.
• Lead incident response activities, investigations, root‑cause analysis, and remediation efforts.
• Develop, maintain, and enforce IT and information security policies, standards, and procedures.
• Support audit readiness, ITGC controls, cybersecurity assessments, and compliance initiatives.

• Provide escalation support for complex technical issues affecting employees and business operations.
• Partner with Human…