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Sr. Director, Digital Portfolio and Strategic Operations

Remote / Online - Candidates ideally in
Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Moderna Therapeutics
Remote/Work from Home position
Listed on 2026-07-13
Job specializations:
  • IT/Tech
    Data Analyst, IT Project Manager
Salary/Wage Range or Industry Benchmark: 210000 - 310000 USD Yearly USD 210000.00 310000.00 YEAR
Job Description & How to Apply Below

Overview

The Senior Director of Digital Operations and Strategic Portfolio Management leads Moderna’s digital initiatives, aligning digital strategy and operations with the company’s priorities. This role partners with the CIO to enable delivery of Moderna's Digital Agenda, focusing on data-driven portfolio leadership, cross-functional programs, and organizational change within the digital organization and beyond. The position is based in Cambridge, MA with onsite work >70% and up to 30% remote work, and may require up to 20% travel primarily to Seattle, WA.

Responsibilities
  • Act as a functional champion in Moderna’s Long Range Planning process, integrating data analytics to align digital efforts with business priorities and corporate goals.
  • Formulate and manage a data-centric business investment strategy grounded in value and risk analysis.
  • Navigate and influence the digital operations strategy within a matrixed organization using data as the foundation for decision-making.
  • Reconcile competing digital priorities by leveraging data insights to ensure cohesion with broader corporate imperatives and adapt strategies as needed.
  • Drive functional and cross-functional strategic digital initiatives, grounded in data and aligned with the company’s mission and vision.
  • Lead program management and organizational change within digital operations, advocating for data-driven methodologies and advanced analytics.
  • Advance digital operations and strategic portfolio management with emphasis on delivery, innovation, operational analytics, and strategic alignment.
  • Partner cross-functionally with other portfolio leaders to improve communication, share best practices, and standardize portfolio/PMO approaches.
  • Articulate a clear digital strategy and roadmap in alignment with the CIO and Digital Leadership Team, supported by data analytics to monitor progress toward targets.
  • Manage the financial aspects of digital projects with data-driven budgeting, cost control, and value realization (ROI).
  • Develop an operational data platform to communicate progress and support informed decision-making.
  • Establish and maintain data-driven KPIs and dashboards to measure and improve digital operations performance.
  • Facilitate regular data-driven leadership meetings to keep the digital operations model in sync with strategic initiatives.
  • Create and uphold governance standards, using data to ensure compliance and effective risk management.
  • Lead a small, ambitious team to meet the Digital organization’s strategic and portfolio/PMO needs, fostering a culture of belonging, development, and innovation.
Qualifications
  • Basic Requirements: BA/BS degree in Information Technology, Business Administration, or related field. 10+ years of experience in digital operations or IT management and strategic planning, with a track record in digital strategy execution and portfolio management. Proven experience in leading digital transformation and managing large-scale technology projects.
  • Preferred Requirements:
    Advanced degree (MA/MS/MBA) in Information Technology, Business Administration, or related field. Exceptional leadership and change-management skills. Experience leading strategic AI initiatives and/or cloud transformation. Strong analytical and strategic planning capabilities with solid financial acumen. Proficiency in project management tools and agile methodologies. Excellent communication skills to engage diverse teams and stakeholders.
Pay & Benefits
  • Competitive healthcare, voluntary benefit programs, and a holistic well-being program including fitness, mindfulness, and mental health support.
  • Family planning benefits including fertility, adoption, and surrogacy support.
  • Generous paid time off, volunteer days, sabbatical, global recharge days, and discretionary year-end shutdown.
  • Savings and investment programs for future planning. Location-specific perks and extras.
Location & Model

Location:

Cambridge, MA. Moderna supports a 70/30 in-office to remote work model with onsite presence required more than 70% of the time. Travel up to 20% may be required.

About Moderna

Moderna is advancing mRNA technology with a mission to deliver transformative medicines. We foster a culture of belonging and aim to build the world’s leading mRNA platform while recognizing our commitments to patients, employees, the environment, and communities.

Equal Opportunities and Accommodations

Moderna is an equal opportunity employer and provides reasonable accommodations for applicants with disabilities. If accommodations are needed during the application process, contact leavesan or .

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