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Sr. Director, Digital Portfolio and Strategic Operations

Remote / Online - Candidates ideally in
Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: BioSpace
Remote/Work from Home position
Listed on 2026-07-14
Job specializations:
  • IT/Tech
    Data Analyst, Change Management
Salary/Wage Range or Industry Benchmark: 196700 - 353400 USD Yearly USD 196700.00 353400.00 YEAR
Job Description & How to Apply Below

Overview

Senior Director of Digital Operations and Strategic Portfolio Management at Moderna will serve as a pivotal force multiplier, driving the execution of strategic digital initiatives and ensuring alignment with the broader operational priorities of the company.

Location & Travel

Based at Moderna’s headquarters in Cambridge, MA. Requires onsite presence >70% of the time with up to 30% flexibility to work from home. Travel up to 20%, primarily to Seattle, WA.

Data-Driven Strategy
  • Act as a functional champion in Moderna’s Long Range Planning (LRP) process, integrating data analytics to align digital efforts with business priorities and corporate goals.
  • Formulate and manage a data-centric business investment strategy that underpins business decisions with robust analysis of value and risk.
  • Navigate and influence the digital operations strategy within a matrixed organization using data as the cornerstone for decision‑making.
  • Reconcile competing digital priorities by leveraging data insights, ensuring cohesion with Moderna’s broader strategic imperatives.
Operational Execution
  • Drive functional and cross‑functional strategic digital initiatives, grounded in data and aligned with the company’s mission and vision.
  • Lead program management and organizational change within the digital operations domain, advocating for data‑driven methodologies and advanced analytics.
  • Propel digital operations and strategic portfolio management with a focus on delivery, innovation, and operational analytics.
  • Partner cross‑functionally with other portfolio leaders across Moderna to share best practices and create consistent governance approaches.
Operations Management
  • Articulate a clear digital strategy vision and roadmap, supported by data analytics to monitor progress and achieve strategic targets.
  • Manage the financial aspects of digital projects with a data‑driven approach to budgeting, cost control, and value realization (ROI).
  • Develop an operational data platform that serves as the engine for communicating organizational progress.
  • Establish and maintain data‑driven KPIs and dashboards to measure, report, and enhance digital operations performance.
  • Facilitate regular data‑driven leadership meetings to keep the digital operations model aligned with strategic initiatives.
  • Create and own governance standards, using data to ensure compliance and effective risk management.
People Leadership
  • Lead a small, ambitious team to meet the strategic and portfolio/PMO needs of the Digital organization.
  • Create a culture of belonging, development, and innovation that nurtures growth for each team member.
Basic Requirements
  • BA/BS degree in Information Technology, Business Administration, or related field.
  • 10+ years of experience in digital operations or IT management and strategic planning, with a track record in digital strategy execution and portfolio management.
  • Proven experience in leading digital transformation and managing large‑scale technology projects.
Preferred Requirements
  • Advanced degree (MA/MS/MBA) in Information Technology, Business Administration, or a related field.
  • Exceptional leadership skills with the ability to foster innovation and manage change within a dynamic environment.
  • Experience leading strategic AI initiatives and/or cloud transformation.
  • Strong analytical and strategic planning capabilities, coupled with solid financial acumen.
  • Proficiency in project management tools and methodologies, including agile practices.
  • Excellent communication skills, with the capacity to engage effectively with diverse teams and stakeholders.
Pay & Benefits
  • Competitive healthcare and voluntary benefit programs.
  • Holistic well‑being approach with access to fitness, mindfulness, and mental health support.
  • Family planning benefits, including fertility, adoption, and surrogacy support.
  • Generous paid time off, including vacation, volunteer days, sabbatical, and global recharge days.
  • Savings and investments to help plan for the future.
  • Location‑specific perks and extras.

The salary range for this role is $ – $. The range reflects the lowest to highest compensation fit for this position at the time of posting. Eligibility for discretionary bonuses, incentive…

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