Senior Clinical Project Manager - Inflammation​/Phase 2b; Sponsor-Dedicated​/Remote -U.S

Senior Clinical Project Manager – Inflammation / Phase 2b

Sponsor Dedicated | Remote (U.S.

-Based). Preference for Hybrid Foster City, CA-Based Candidates.

Are you a senior clinical operations professional who knows how to independently lead complex global clinical trials from start‑up through closeout – while staying deeply connected to the operational details that drive execution success?

This is a highly visible opportunity supporting large‑scale global Phase 2b inflammation programs within a sponsor‑dedicated environment. The ideal candidate brings both strategic global‑trial leadership and a hands‑on operational mindset – someone who can confidently lead international cross‑functional teams, oversee global vendors and CROs, and still comfortably work "in the weeds" to proactively solve problems, remove roadblocks, and keep studies moving forward.

This role is best suited for a Senior Clinical Project Manager who thrives in fast‑paced, high‑accountability environments where timelines move quickly, priorities shift often, and strong execution is critical. You will play a central role in driving operational excellence across complex global studies spanning multiple regions and stakeholders.

• Independently lead complex global clinical trials from study start‑up through database lock and closeout.
• Drive operational execution across multiple international regions while maintaining alignment to global study strategy and timelines.
• Maintain deep operational oversight across all aspects of study execution – this is not a "high‑level only" oversight role.
• Operate effectively both strategically and tactically, balancing big‑picture program leadership with hands‑on operational involvement.
• Proactively identify global operational risks, regional challenges, and study execution issues while driving resolution plans forward.
• Ensure study deliverables, milestones, and timelines remain on track within fast‑paced development environments.
• Lead global study execution efforts across cross‑functional stakeholders, vendors, CROs, and regional teams.

• Provide strong oversight and accountability management for global CROs and external vendors.
• Lead vendor governance discussions, escalation management, and performance oversight activities.
• Drive operational follow‑through and execution accountability across external partners.
• Contribute to vendor strategy, resourcing discussions, and operational planning activities.
• Navigate complex global vendor relationships across multiple regions and time zones.

• Lead large, matrixed global cross‑functional teams within highly collaborative clinical development environments.
• Facilitate effective meetings with clear agendas, decision‑making, accountability, and follow‑up.
• Build strong partnerships across Clinical Operations, Data Management, Regulatory, Safety, Medical, and external stakeholders.
• Communicate confidently with senior leadership while effectively managing competing priorities and stakeholder expectations.
• Mentor junior team members and contribute to a collaborative, solutions‑oriented team culture.

• Oversee development and review of key study documents including protocols, informed consents, monitoring plans, investigator brochures, and clinical study reports.
• Support global study planning, forecasting, budget management, and resource coordination.
• Review operational metrics, study data listings, enrollment trends, and study performance indicators.
• Ensure alignment across regional operational requirements and global study objectives.
• Contribute to process improvement initiatives, SOP development, and operational best practices.

• Significant Clinical Operations and global clinical trial management experience within CRO, biotech, or pharmaceutical environments.
• Proven success independently leading complex global clinical trials from start‑up through closeout.
• Strong experience managing large‑scale international studies across multiple global regions.
• Demonstrated expertise leading global cross‑functional teams and…