Project Manager II - Inflammation​/Phase 2b; Sponsor-Dedicated​/Remote -U.S

Project Manager II - Inflammation/ Phase 2b (Sponsor Dedicated - Remote; Preference for Hybrid Foster City, CA)

Are you a clinical project management professional who knows how to take ownership of a study from start-up through closeout - not just oversee it from a distance, but truly drive execution day-to-day? This highly visible opportunity supports a complex Phase 2b inflammation program within a fast‑paced sponsor‑dedicated environment where strong operational leadership, accountability, and execution matter. The ideal candidate is comfortable operating both strategically and tactically – someone who can lead cross‑functional teams while also rolling up their sleeves and working in the details to keep a study moving forward.

If you thrive in high‑accountability environments, can navigate ambiguity, and enjoy being deeply involved in clinical trial execution from start to finish, this role offers the opportunity to make a direct impact.

While remote/home‑based candidates may be considered, priority will be given to candidates located in or near Foster City, California, with the ability to work onsite 2‑3 days per week.

• High‑impact role supporting a complex Phase 2b inflammation study
• Opportunity to lead regional execution efforts within a large global clinical program
• Strong visibility across Clinical Operations, leadership, and external partners
• Fast‑moving environment where decisions and execution happen quickly
• Significant ownership and autonomy with the expectation to independently drive study progress
• Collaborative sponsor‑dedicated culture with supportive leadership and strong team partnership
• Opportunity to work alongside highly experienced clinical operations professionals in a hands‑on environment

• Drive operational execution of a complex Phase 2b inflammation study from study start‑up through database lock and closeout
• Independently manage day‑to‑day study operations with minimal oversight
• Own timelines, deliverables, risks, and issue resolution across multiple work streams
• Maintain deep operational awareness across all aspects of the trial – this is a role for someone comfortable working “in the weeds”
• Ensure study milestones stay on track in a fast‑paced environment with shifting priorities and competing demands
• Partner cross‑functionally to proactively identify risks, remove roadblocks, and implement operational solutions quickly

• Lead vendor management activities and maintain strong oversight of external partners and CROs
• Contribute to RFP development, vendor selection, and ongoing vendor performance management
• Hold vendors accountable to timelines, deliverables, quality expectations, and issue resolution
• Actively manage operational follow‑through rather than relying solely on escalation pathways

• Lead cross‑functional meetings with clear agendas, action‑oriented discussions, and strong follow‑up
• Drive accountability across internal teams and external partners
• Build strong collaborative relationships while effectively navigating challenging conversations and competing priorities
• Mentor or support junior team members as needed
• Operate confidently within a matrixed global environment with multiple stakeholders

• Draft, review, and coordinate key study documents including protocols, informed consents, monitoring plans, investigator brochures, and clinical study reports
• Support study budget tracking, forecasting, and operational planning activities
• Review data listings and support interim/final reporting activities
• Train CROs, investigators, study coordinators, and vendors on protocol and study requirements
• Contribute to SOP development, process improvement initiatives, and operational best practices

• 3+ years of clinical project management experience within clinical research
• Experience running clinical trials from start‑up through closeout, with a strong understanding of the full clinical trial lifecycle
• Experience supporting complex Phase 2b studies within the inflammation therapeutic area
• Strong CRO/vendor management and…