Senior Clinical Project Manager - Oncology​/Hematology; Phase III ; Remote - US​/Canada

Senior Clinical Project Manager – Oncology/Hematology (Phase III) (Remote – US/Canada)

Are you a seasoned CRO project leader passionate about advancing oncology and hematology research? Do you thrive in a fast‑paced, collaborative environment where your leadership directly impacts patient outcomes? Join our team as a Senior Project Manager and take ownership of complex Phase III trials, driving projects from proposal through delivery and shaping the future of cancer care.

As a Senior Project Manager, you will take a lead role in advancing Phase III oncology and hematology clinical trials, managing complex, global initiatives. You'll lead and inspire cross‑functional teams, mentor emerging project managers, and act as the primary strategic partner for our clients, ensuring every milestone is delivered on time, on budget, and with exceptional quality.

• Drive the operational and financial success of Phase III clinical trials.
• Lead cross‑functional teams across Clinical Operations, Regulatory Affairs, Data Management, Biostatistics, Medical Affairs, Pharmacovigilance, and QA.
• Act as the primary liaison with clients, ensuring smooth project launch, conduct, and closeout.
• Oversee project deliverables, timelines, and budgets while proactively identifying and mitigating risks.
• Mentor junior project managers and project support staff, fostering collaboration and professional growth.

• Own project budgets, forecasts, and financial performance.
• Ensure alignment and accountability across all vendors and study partners.
• Implement contingency plans and risk mitigation strategies to keep projects on track.

• Maintain and evaluate project progress using advanced tracking tools.
• Prepare and present project materials for internal and external stakeholders.
• Support inspection readiness and Trial Master File compliance.

• Participate in bid defense meetings as the potential project lead.
• Build strong client relationships to generate new opportunities.
• Stay up‑to‑date on oncology/hematology trends and the evolving drug development landscape.

• Train and mentor new project managers and clinical staff.
• Facilitate team communication, collaboration, and professional development.

• Experienced Global Project Leader with strong Phase III CRO project management experience and a proven track record of delivering clinical trials successfully.
• Oncology and Hematology expertise, with direct experience leading complex Phase III trials.
• Cross‑functional team leadership, overseeing teams such as Clinical Operations, Regulatory Affairs, Data Management, Biostatistics, Medical Affairs, Pharmacovigilance, and QA.
• Financial savvy, skilled in managing multi‑million‑dollar budgets, including creation, forecasting, and negotiation of out‑of‑scope work.
• Vendor management expertise, ensuring alignment, quality, and accountability across all study partners.
• Deep regulatory knowledge, with expertise in GCP/ICH guidelines and other applicable regulatory requirements.
• Educational foundation:
  Bachelor’s degree in Life Sciences, Medicine, Pharmacy, Nursing, or a related field.
• Tech‑forward, comfortable leveraging digital tools and emerging technologies to optimize project delivery.
• Strategic, results‑driven leader with exceptional communication skills, able to navigate complex, dynamic environments while inspiring teams to achieve excellence.

• Highly collaborative, innovative, and performance‑driven team.
• Opportunities to mentor and be mentored, helping you grow professionally while developing others.
• Work on impactful global oncology and hematology trials, shaping the future of patient care.
• Environment where innovation, growth, and professional development are actively encouraged.

If you are ready to lead high‑impact Phase III oncology and hematology clinical trials, drive innovation, and make a real difference in patient outcomes, we want to hear from you!

The base salary range represents the anticipated low and high of the Syneos Health range for this position.…