Cardiovascular Research Scientist

Position Overview

Pivot Path Solutions is seeking a Cardiovascular Research Scientist / Physiologist to support advanced research and development efforts in digital twin technologies for predictive medicine. This role will focus on developing and validating physiology-based models of the cardiovascular system
, integrating clinical data with computational methods to simulate disease progression and treatment outcomes.

The ideal candidate brings deep expertise in cardiovascular physiology, hemodynamics, and computational modeling
, with the ability to translate biological systems into predictive, data-driven models. This position will play a critical role in supporting high-impact R&D initiatives aligned with federal research programs. This is a remote position.

• Develop high-fidelity physiological models of the cardiovascular system, including blood flow dynamics, cardiac function, and systemic responses
• Translate clinical and experimental data (e.g., imaging, vitals, lab values) into computational models
• Support the design of digital twin architectures for patient-specific modeling

• Build and validate mechanistic (physics-based) models of:
  • Hemorrhage and shock (acute conditions), OR
  • Heart failure and chronic cardiovascular disease
• Collaborate on the development of reduced-order models (ROMs) for real-time simulation
• Conduct sensitivity analysis, uncertainty quantification, and model calibration

• Collaborate with clinicians to ensure biological and clinical relevance of models
• Support development of validation strategies
  , including comparison against human or animal data
• Contribute to study design and experimental protocols as needed

• PhD in:
  • Biomedical Engineering
  • Physiology
  • Cardiovascular Science
  • Computational Biology or related field
• Strong background in cardiovascular physiology and hemodynamics
• Demonstrated ability to work with multimodal biomedical data
• Experience with peer-reviewed publications or funded research projects

• Collaborate on high-impact federal innovation programs.

• Flexible, entrepreneurial engagement model.

• Opportunity to shape next-generation digital twin initiatives in mission-critical environments.

• Direct access to executive leadership and capture strategy discussions.