Senior Clinical Project Manager - Inflammation​/Phase 2b; Sponsor Dedicated - Remote; Preferenc

Job Responsibilities

Are you a senior clinical operations professional who knows how to independently lead complex global clinical trials from start-up through closeout—while still staying deeply connected to the operational details that drive execution success?

This is a highly visible opportunity supporting large‑scale global Phase 2b inflammation programs within a sponsor‑dedicated environment, as a U.S.

-based Global Study Lead. These pivotal programs span North America, Europe, APAC, Japan, and China, offering the opportunity to lead large‑scale international clinical trials with significant visibility and impact.

We are seeking an experienced Senior Clinical Project Manager / Global Study Lead with a proven track record of leading pivotal global Phase 2b studies and driving trial execution with minimal oversight. Operating within a small, highly collaborative team, the successful candidate will bring demonstrated experience leading complex global programs, driving cross‑functional accountability, navigating operational challenges, and delivering results in a matrixed environment.

This role is ideal for a seasoned clinical project leader who thrives in a high‑ownership environment, is comfortable making critical decisions, influencing stakeholders, and taking full accountability for the successful delivery of global clinical trials.

While remote/home‑based candidates may be considered, priority will be given to candidates located in or near Foster City, California, with the ability to work onsite 2‑3 days per week.

• Lead pivotal, highly complex global Phase 2b inflammation studies
• Serve as Global Study Lead across North America, Europe, APAC, Japan, and China
• Operate with significant ownership and autonomy in a sponsor‑dedicated environment
• Join a lean, highly collaborative team where independent leadership and sound decision‑making are valued
• Partner directly with Sponsor stakeholders and senior leadership
• Play a visible role in the successful execution of critical clinical development programs
• Influence study strategy while maintaining hands‑on operational leadership
• Contribute to globally significant programs with meaningful impact on patient care and drug development

• Serve as the Global Study Lead for complex, pivotal Phase 2b inflammation studies
• Lead global study execution across North America, Europe, APAC, Japan, and China
• Provide strategic and operational leadership throughout study start‑up, conduct, and close‑out
• Act as the primary point of accountability for study delivery, quality, timelines, and execution
• Lead cross‑functional global teams and drive alignment across internal stakeholders, vendors, and external partners
• Manage interdisciplinary clinical research programs in compliance with GCP, ICH guidelines, SOPs, and applicable regulatory requirements
• Serve as the primary liaison between the Sponsor and project stakeholders throughout the study lifecycle
• Maintain accountability for study deliverables, milestones, risks, budgets, and overall project performance
• Independently drive decision‑making and execution while ensuring stakeholder alignment and operational excellence

• Coordinate activities and deliverables across CROs, vendors, and project partners
• Lead proactive risk identification, mitigation planning, and issue resolution activities
• Maintain oversight of project timelines, study trackers, key milestones, and critical deliverables
• Oversee inspection readiness activities, including Trial Master File strategy and oversight
• Ensure implementation of project plans in accordance with study requirements and controlled documents
• Anticipate operational challenges and independently develop solutions to maintain study timelines and quality standards
• Drive accountability across study teams to ensure successful execution and delivery

• Lead global cross‑functional teams and foster a culture of accountability, collaboration, and performance
• Independently prepare, coordinate, and present project materials during Sponsor, governance, and executive‑level meetings
• Facilitate project‑related…