Principal Statistical Associate - Biostatistics

Job Title:

Principal Statistical Associate - Biostatistician

Job Description

We are seeking a Principal Statistical Associate - Biostatistician to lead statistical analyses on diverse clinical research projects. You will collaborate with sponsors, external investigators, and internal project team members on a variety of federal research projects, including Phase 1-4 randomized clinical trials. You will design cutting-edge studies, conduct data analysis, and contribute to scientific peer-reviewed publications. This role involves presenting computational and statistical analysis results, assisting with data access, analysis, and interpretation, and building algorithms to answer clinical and epidemiologic questions.

Responsibilities

+ Lead and support the development and review of study protocols, focusing on Bayesian methods.

+ Develop study aims, research hypotheses, and assess feasibility.

+ Estimate optimal sample size for desired power while considering resource limitations.

+ Develop statistical considerations and analysis methods for study protocols.

+ Create statistical analysis plans and guide data management teams.

+ Oversee and consult on analytical programming, data management, and quality control.

+ Conduct statistical analysis for clinical trials, studies, and projects.

+ Research, recommend, and implement methods to validate and interpret results.

+ Participate in quality control and review code output, tables, and charts.

+ Present analytic results to internal and external audiences with context.

+ Serve as a data resource for research project teams and interact with clients.

Essential Skills

+ Proficiency in Bayesian Methods, R, and SAS.

+ Experience in clinical trial design, Bayesian biostatistics, and adaptive designs.

+ Ability to perform sample size and power calculations.

+ Hands-on experience in statistical programming and clinical data analysis.

+ Proven statistical leadership and study design consulting skills.

Additional

Skills & Qualifications

+ PhD in Biostatistics or a related quantitative field with 5 years of post-doctoral relevant experience.

+

Experience with health research, advanced data analysis, and statistical packages.

+ Skill and expertise in a broad range of statistical methods for clinical trials.

+ Knowledge of Bayesian adaptive and SMART designs.

+ Ability to plan, develop, and present statistical analysis plans.

+ Capability to work in study teams and guide others in statistical methods.

Work Environment

This role is a hybrid position requiring work onsite at our Bethesda, Maryland office 2 days per week, with the flexibility to work from your home office 3 days per week. This position supports government-funded clinical research trials.

Job Type & Location

This is a Contract position based out of Bethesda, MD.

Pay and Benefits

The pay range for this position is $50.00 - $60.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

- Medical, dental & vision
- Critical Illness, Accident, and Hospital - 401(k) Retirement Plan
- Pre-tax and Roth post-tax contributions available
- Life Insurance (Voluntary Life & AD&D for the employee and dependents) - Short and long-term disability
- Health Spending Account (HSA) - Transportation benefits
- Employee Assistance Program
- Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a hybrid position in Bethesda,MD.

Final date to receive applications

This position is anticipated to close on Aug 10, 2026.

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