Director, Clinical Science – Oncology Clinical Development

Director, Clinical Science – Oncology Clinical Development

Cancer is unrelenting, but so are we. At GSK, we are committed to transforming outcomes for people with cancer through innovative science, bold ambition, and strong partnerships across the healthcare ecosystem. We focus our science where it can matter most—advancing care in cancers with high unmet need, grounded in a deep understanding of disease biology and deliberate scientific choices that connect discovery to meaningful impact in the real world.

The Director, Clinical Science – Oncology Clinical Development provides scientific leadership across defined components of study design, conduct, data review, and interpretation within an assigned clinical programme. Reporting to the Clinical Development Lead (CDL), this role operates within the asset-level clinical strategy and contributes scientific depth and rigour to the execution of the Clinical Development Plan (CDP).

The Director, Clinical Scientist partners closely with the Senior Scientist and cross-functional teams to support delivery of clinical studies, ensuring scientific quality, data integrity, and robust interpretation of clinical data. This role contributes to both study-level activities and broader programme insights, without holding accountability for asset-level strategy or overall study delivery.

This is a scientific individual contributor role requiring deep oncology clinical development expertise, strong analytical and collaboration skills, and the ability to operate effectively within a complex, matrixed environment.

In This Role You Will:

• Provide scientific leadership across defined components of study-level activities, including protocol development, study design, data review, and interpretation, within the strategic direction set by the CDL
• Serve as a core member of the Clinical Matrix Team (CMT), ensuring scientific alignment across study objectives, timelines, and deliverables
• Provide scientific insight to the CDL and Senior Scientist to inform asset-level strategy, benefit–risk assessment, and programme-level decision-making
• Ensure the scientific quality and consistency of key clinical and regulatory documents, including protocols, Investigator's Brochures, Clinical Study Reports, and submission materials
• Apply scientific and clinical expertise to analyse and interpret data, ensuring rigour, integrity, and relevance to the target patient population
• Engage with internal and external stakeholders, including investigators and Key External Experts, to support study execution and scientific exchange
• Contribute to a culture of scientific excellence, innovation, and continuous improvement within Oncology Clinical Development

Why You? Working model:

This role is hybrid. You will be on-site at one of the posted locations at least two days per week. Remote work is available on other days.

Basic Qualifications We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• Bachelor's degree in life sciences or related scientific discipline required
• Experience in pharmaceutical/biotechnology industry or related clinical development experience, with a focus on oncology.
• Experience in clinical development from early stage through to regulatory submission, including study design, protocol authoring, and data review/interpretation.
• Experience working within GCP, ICH, and global regulatory guidelines.
• Experience authoring or contributing to clinical study proposals, protocols, Investigator's Brochures, informed consent forms, clinical study reports, and regulatory submissions.
• Experience working within cross-functional matrix teams and contributing to clinical decision-making.
• Proven track record of working with investigators, site staff, external experts, CROs, and vendors.

Preferred Qualifications If you have the following characteristics, it would be a plus:

• Advanced degree (e.g. MS, PhD, PharmD) strongly preferred in life sciences or a related discipline
• Clinical development experience across multiple phases of development (Phase I–IV)
• GU Oncology or immuno-oncology clinical development experience.
• Experience presenting or preparing materials for Protocol Review Boards, governance meetings, or scientific forums.
• Knowledge of regulatory requirements to support registration, including experience contributing to IND, EoP2, scientific advice, pre-NDA/BLA, NDA/MAA, or AdCom submissions.