Remote Biology Research Scientist: Target Validation Job Washington District of Columbia USA,Research/Development

Biology Research Scientist

Job Type: Contractor
Location: Remote
Hours: 10–20 hours/week
Duration: 1–2 months minimum, with likely extension
Start: Immediate

Job Overview

We are seeking experienced Biology Research Scientists to support a project focused on validating protein target assignments against primary scientific sources and Uni Prot records.

You will review research papers and patents, identify target assignment errors, propose corrected Uni Prot accessions, and provide concise, evidence-based scientific reasoning.

Key Responsibilities

Review primary research papers and patents to verify protein target assignments.
Compare target assignments against Uni Prot and identify discrepancies.
Classify target assignment errors using a structured taxonomy.
Propose accurate Uni Prot accessions where assignments are incorrect.
Document clear, concise, evidence-grounded reasoning for each determination.
Apply expertise in pharmacology, biochemistry, molecular biology, or chemical biology to evaluate target relationships.

Required Skills

Protein Target Identification
Uni Prot
Primary Literature Review
Protein Biochemistry
Molecular Biology
Pharmacology
Binding & Functional Assays
Scientific Data Interpretation
Evidence-Based Reasoning
Technical Documentation

Qualifications

BA/BS + 5 years
, MS + 2 years
, or PhD with relevant industry/drug discovery experience
.
Background in pharmacology, biochemistry, molecular biology, or chemical biology within biotech, pharma, or CRO environments.
Hands-on experience with assays such as SPR, TR-FRET, radioligand binding, kinase assays, or GPCR functional assays
.
Experience interpreting IC50, Ki, and Kd data.
Currently active in a bench-based research, scientist, or associate scientist role.
Working knowledge of Uni Prot or related workflows such as SAR, HTS, target validation, biochemical profiling, or IND-enabling studies
.

Nice to Have

Experience with ChEMBL, BindingDB, or Pub Chem
.
Selectivity profiling or counter screening experience.
Understanding of agonist/antagonist vs. activator/inhibitor distinctions.

Screening Questions

What is your highest relevant degree and how many years of industry research experience do you have?

What is your experience with protein target identification and Uni Prot?

Which binding or functional assays have you performed hands-on?

Do you have experience interpreting IC50, Ki, or Kd data?

Have you worked with ChEMBL, BindingDB, or Pub Chem?

Are you currently bench-active in a research or scientist role?

Are you available for 10–20 hours per week with an immediate start?

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