Senior Scientist, Analytical Development & Quality Control; ADQC

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

Seeking an experienced analytical chemist to join our Analytical Development & Quality Control (ADQC) group at the Research Associate II level. The ideal candidate will be familiar with HPLC and other chemistry techniques, possess a strong work ethic and strong technical background, demonstrate excellent oral and written communication skills, and have experience working in a GMP environment. The successful candidate will be able to perform the following responsibilities with a high degree of independence and attention to detail.

• Conduct routine and non‑routine analysis of Raw and Starting material samples
• Review analytical data for compliance to SOPs
• Assemble and document data for quality review
• Present and participate in internal and external scientific meetings
• Revise and update SOPs as needed (e.g., analytical methods, equipment procedures, and material specifications)
• Conduct analytical investigations
• Apply knowledge of cGMP and GLP
• May develop and/or optimize analytical methods
• May author sections of scientific reports

• BS or MS degree in Chemistry or related field
• 2+ years of experience in analytical development and quality control role
• Practical knowledge of HPLC, MS, and GC, including operation of instrumentation
• Familiarity with GMP requirements, with hands‑on GMP experience preferred
• Experience following SOPs and recording data in laboratory notebooks or data collection forms
• Ability to interpret experimental results and demonstrate good judgement in resolving issues / making recommendations
• Detail oriented with strong organizational skills
• Excellent written and verbal communication skills
• Ability to manage priorities and maintain aggressive timelines for multiple projects

Please visit our website,  for more information about Ionis and to apply for this position; reference requisition #IONIS
003987

Ionis offers an excellent benefits package! Follow this link for more details:
Ionis Benefits

Full Benefits Link:

The pay scale for this position is $71,219 to $90,448

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.