Senior Scientist, Chemistry at Merck South San Francisco, CA

Senior Scientist, Chemistry job th San Francisco, CA.

Our Company is seeking exceptional chemists for positions within the Discovery Chemistry Department. The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying innovative synthetic chemistry, analytical techniques, and data analysis to design and synthesize drug candidates and intermediates. In addition, you'll have the opportunity to expand your knowledge and skills through collaborations with talented and dedicated colleagues while advancing your career.

To accomplish the above, the successful candidate must be a creative and innovative scientist with strong organic synthesis, problem solving, interpersonal, collaboration and communication skills.

• Act as an expert in the laboratory, executing on program and chemistry strategy.
• Develop and utilize innovative synthetic, medicinal chemistry and/or chemical biology problem solving skills coupled with analysis of diverse data sets to build structure-activity relationships.
• Design, synthesize, purify, and characterize drug candidates and/or chemical probes in target identification and validation, hit-to-lead, and lead optimization programs.
• Provide scientific mentoring and technical training of team members.
• Establish a substantial external scientific presence including authoring significant scientific publications and presentations.

• B.S in chemistry, medicinal chemistry, or related scientific discipline with seven (7) years' experience, M.S. in related fields with four (4) years' experience, or a Ph.D. in related fields (received by Summer 2026) with 0-2 years' experience.

• Extensive experience in organic synthesis with emphasis on methodology/catalysis, total synthesis, and/or physical organic chemistry.
• Ability to solve complex problems.

• Accountability
• Adaptability
• Analytical Method Development
• Chemical Proteomics
• Chemical Synthesis
• Chemometrics
• Chromatography
• Data Analysis
• Data-Driven Decision Making
• Flow Cytometry
• Machine Learning (ML)
• Mass Spectrometry Based Proteomics
• Motivation Management
• Process Analytical Technology (PAT)
• Protein Chromatography
• Spectroscopy
• Synthetic Biology

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment.

We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday
- Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based,…