Associate Director, Clinical Development - Neurology

Associate Director, Clinical Development
- Neurology

Job Category: Development
- Ionis

Requisition Number: IONIS
004080

• Posted :
  July 24, 2026
• Full-Time

Showing 1 location

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

The Associate Director, Clinical Development – Neurology provides clinical development leadership and scientific expertise to one or more project teams, supporting the successful design and execution of development plans for Ionis’ investigational assets. Near‑term responsibilities focus on leading key aspects of Ionis‑sponsored clinical trials, clinical data analysis and interpretation, communication of project information and risks, and contributions to regulatory submissions, publications, and presentations.

Over time, the role may have opportunities to contribute to broader clinical development strategy and clinical trial design.

This position sits within the neurology franchise (including rare diseases). The primary focus will be neurology, including neuromuscular diseases, neurodegenerative diseases, and rare pediatric neurogenetic disorders. This position can be fully onsite, remote, or hybrid. For remote employees, periodic travel to Ionis’ headquarters in Carlsbad is expected, approximately once per quarter.

• Serve as the clinical lead for assigned studies, representing Clinical Development in internal and external interactions and helping ensure successful execution of a high‑priority Phase 3 program by:
• Developing and maintaining excellent working relationships with investigators and clinical trial teams
• Delivering high‑quality scientific presentations on company technology, investigational agents, and clinical study issues to investigators and site staff
• Providing guidance and/or training for external personnel involved in Ionis clinical studies
• Performing ongoing review of clinical study data and operational progress
• Identifying emerging risks and partnering with the project team to proactively manage and mitigate them
• Lead and/or contribute to the writing and review of key clinical documents for regulatory submissions (e.g., study protocols, Investigator’s Brochures, IND submissions, Clinical Study Reports).
• Engage internal and external stakeholders (e.g., key opinion leaders, advocacy organizations, regulators) to obtain advice and feedback that informs development plans, trial designs, and study results.
• Communicate project information – including study progress, risks, plans, and recommendations – clearly to…