Senior Bioinformatics Scientist

Position: Senior Staff Bioinformatics Scientist
Location: California

Senior Staff Bioinformatics Scientist page is loaded## Senior Staff Bioinformatics Scientist locations:
Remote-USA-CAtime type:
Full time posted on:
Posted Todayjob requisition :
R-100606
** Company Description
** Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer.

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* Position Summary:

** As a technical leader in bioinformatics and molecular diagnostics, you will drive pivotal initiatives while nurturing the next generation of scientific talent. You will pinpoint strategic opportunities that enhance team capabilities and business outcomes, establishing standards that inspire and guide your colleagues. Leveraging your extensive expertise in software development, regulatory compliance, molecular biology, and quality systems, you will serve as a trusted advisor to scientists throughout the organization.

Your contributions will play a pivotal role in shaping the direction and strategy for the development of new diagnostics and the expansion of production capabilities s initiative will ensure that Guardant remains a leader in the field, fostering a sustainable business model that enhances the lives of patients today and for years to come.
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* Essential Duties and Responsibilities:

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* · Partner with Technology Development to design and validate experimental protocols, from initial R&D through regulatory submission
· Architect and enhance bioinformatics algorithms that power both new diagnostic development and existing production workflows
· Lead technical initiatives hands-on while mentoring teams in building robust, scalable bioinformatics pipelines
· Develop data management strategies that optimize product performance and empower cross-team collaboration
· Drive strategic decisions by evaluating cost-benefit analyses for performance improvements and COGS reduction
· Champion innovation by staying current with cutting-edge sequencing technologies and computational methods
· Build consensus across scientific, quality, regulatory, and business teams to align priorities with user needs
· Guide complex projects from conception to completion, anticipating challenges and ensuring timely delivery
· Synthesize and communicate findings effectively, from internal presentations to regulatory submissions and peer-reviewed publications
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* Required Qualifications:

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* · PhD level with 10+ years related industry experience.
· Expert experience with data and statistical analysis with Python.
· Expert developing bioinformatics pipelines in one or more languages (e.g., Python, R, Java, C++, Rust). Comfortable with developing in cloud environments and using workflow managers.
· 5+ years managing and troubleshooting genetic sequencing assays or tests
· Statistical design for experiments for development and validation of diagnostics in a regulated environment (e.g., CAP/CLIA, FDA)
· Ability to design well-tested software that interfaces in larger systems and is extensible by other team members and teams
· Proven mentor and leader of teams that have successfully developed and launched medical diagnostics
** Additional information:
** Hybrid Work Model:
At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires.

At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected…