Molecular Pathologist

Nemours Children's Hospital, Delaware in Wilmington is seeking a Full-Time Molecular Pathologist to join our growing team. The Molecular Pathologist will work within an integrated molecular diagnostics and genomics program supporting the Biobank and Molecular Analysis Program (BMAP) and the Nemours Genomics Laboratory. In addition to providing clinical interpretation of diagnostic assays, the Molecular Pathologist will oversee the development, validation, implementation, and quality management of molecular diagnostic testing, including next-generation sequencing (NGS)–based exome, genome, and targeted panel assays, as well as emerging molecular and genomic technologies.

Nemours Children's Hospital, Delaware in Wilmington is seeking a Full-Time Molecular Pathologist to join our growing team. The Molecular Pathologist will work within an integrated molecular diagnostics and genomics program supporting the Biobank and Molecular Analysis Program (BMAP) and the Nemours Genomics Laboratory. In addition to providing clinical interpretation of diagnostic assays, the Molecular Pathologist will oversee the development, validation, implementation, and quality management of molecular diagnostic testing, including next-generation sequencing (NGS)–based exome, genome, and targeted panel assays, as well as emerging molecular and genomic technologies.

This role is central to establishing compliant, high-quality molecular diagnostic services for pediatric patients while supporting innovative translational research initiatives. Responsibilities include in-house assay design, clinical validation, regulatory compliance, quality program oversight, policy and procedure development, and close collaboration with pathology, clinical, research, and bioinformatics teams in alignment with CAP and CLIA standards.

• Serve as the scientific and clinical lead for molecular pathology and genomics testing within BMAP and the Nemours Genomics Laboratory.
• Direct clinical validation, implementation, and ongoing quality management of NGS-based assays, including somatic and germline testing.
• Provide molecular pathology consultation and interpretation in close collaboration with pediatric subspecialists and pathology colleagues.
• Ensure compliance with CAP, CLIA, New York State requirements if applicable, and institutional regulatory standards.
• Participate in test utilization review, assay performance monitoring, and laboratory readiness for inspections and accreditation.

• Lead the development and validation of in-house NGS panels, including disease-focused, tumor, and pediatric precision medicine applications.
• Drive expansion into rapid whole-exome sequencing, genome-scale assays, and emerging genomics technologies.
• Evaluate and implement novel methodologies such as RNA sequencing, long-read sequencing, methylation profiling, spatial approaches, and multi-omics technologies as clinically and scientifically appropriate.
• Collaborate with bioinformatics teams to ensure robust data analysis, interpretation, and reporting pipelines.

• Support and develop translational research studies leveraging the institutional biobank and molecular platforms.
• Partner with clinician-scientists and investigators on investigator-initiated and grant-funded research programs.
• Contribute to scholarly activity, including publications, presentations, and participation in national or international consortia.
• Facilitate responsible integration of research assays into clinical workflows when appropriate.

• In partnership with BMAP’s Collaborating Research Scientist and Medical Director in mentoring a team of laboratory manager(s) and…