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Automation Service Engineer II; Workcell Assembly & Support

Job in Palo Alto, Santa Clara County, California, 94306, USA
Listing for: Guardant Health
Full Time position
Listed on 2026-02-23
Job specializations:
  • Engineering
    Automation Engineering, Systems Engineer, Electrical Engineering, Manufacturing Engineer
Salary/Wage Range or Industry Benchmark: 108000 - 148500 USD Yearly USD 108000.00 148500.00 YEAR
Job Description & How to Apply Below
Position: Automation Service Engineer II (Workcell Assembly & Support)
** Company Description
** Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer.

For more information, visitand follow the company on,and.## ##
** Job Summary
** Guardant Health is seeking a Senior Automation & Instrumentation Technician to support, maintain, and optimize automated laboratory equipment and instrumentation used in DNA sequencing workflows. This role will be hands-on, requiring the candidate to assemble automated track systems, troubleshoot, maintain, validate, and provide input to continuously improve complex automated systems in a regulated laboratory environment. The ideal candidate will be a strong technical problem-solver who thrives in fast-paced operations and collaborates closely with Engineering, Quality, and Operations teams.##

** Essential

Duties & Responsibilities
*** Provide day-to-day service, support, and troubleshooting of automated laboratory instrumentation and processes at Guardant Health’s facilities.
* Diagnose and resolve complex electromechanical issues to minimize equipment downtime and maintain operational continuity.
* Perform root cause analysis on instrument failures associated with Guardant’s DNA sequencing products and implement corrective actions.
* Triage equipment issues and coordinate with vendors and external service providers as needed.
* Assemble and install electromechanical components, subsystems, control panels, safety circuits, and automated machinery based on engineering drawings and technical specifications.
* Author, update, and maintain all standard operating procedures (SOPs), work instructions (WKI), and technical documentation for new product assemblies, equipment operation, and maintenance.
* Perform Installation Qualification (IQ), Operational Qualification (OQ), and Process Qualification (PQ) on new and existing equipment.
* Execute testing and validation activities to verify equipment performance, accuracy, and reliability.
* Identify, troubleshoot, and resolve issues identified during installation and validation activities.
* Perform routine, corrective, and preventive maintenance on laboratory automation and instrumentation.
* Develop, execute, and improve preventive maintenance schedules to ensure optimal equipment performance.
* Support equipment upgrades and modifications as required to meet operational needs.
* Maintain accurate and organized equipment records, maintenance logs, and validation documentation.
* Partner with Quality to ensure all documentation meets regulatory and quality system requirements.
* Identify opportunities to improve equipment reliability, usability, and operational efficiency.
* Recommend practical process improvements and assist with execution of improvement initiatives.
* Represent the Automation Service Engineering department in cross-functional meetings, providing technical input from an equipment support perspective.
* Support special projects and operational initiatives, as assigned.
* Provide hands-on training and mentorship to junior technicians and operators.
* Follow established safety procedures and quality standards during all maintenance, testing, and installation activities.
* Proactively identify potential safety risks and support corrective actions.
* Work effectively within a team environment and build strong working relationships across departments.
* Participate in an on-call rotation supporting lab operations after-hours.##
** Required Qualifications
*** Technical degree in Electrical or Mechanical Engineering, Mechatronics systems, or equivalent experience.
* 3+ years of experience supporting automated laboratory equipment, instrumentation, or electromechanical systems and/or 5+…
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