Sr. Clinical Data Scientist

Career Opportunities with Summit Therapeutics Sub, Inc.

A great place to work.

Careers At Summit Therapeutics Sub, Inc.

Current job opportunities are posted here as they become available.

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people.

Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

• HARMONi:
  Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.
• HARMONi-3:
  Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
• HARMONi-7:
  Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.
• HARMONi-GI3:
  Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

Summit is seeking a highly motivated Sr. Clinical Data Scientist to join our growing team. This role will be instrumental in advancing our technology-enabled and data-driven clinical data review and study monitoring strategy through automation, analytics, and cross-functional data support.

The ideal candidate will be proficient in R and/or Python and apply these skills across clinical data domains to enhance processes, increase efficiency, and elevate data quality. A strong focus on workflow optimization, coupled with a passion for implementing technical solutions in a fast-paced pharmaceutical environment, will be essential for success.

• Develop clinical study reports, dashboards, and data visualizations using R or Python.
• Partner closely with the Data Management team to implement data-monitoring or reconciliation listings and edit checks that support ongoing data review.
• Collaborate with Clinical Operations to generate study metrics and identify potential site-level risks.
• Communicate requirements clearly with vendors, author and curate specs, and ensure the results delivered by vendors.
• Perform data wrangling and data processing in R/Python to support the summarization and interpretation of clinical trial data.
• Build ETL pipelines in a Windows environment to automate clinical data workflows and streamline clinical programming activities.
• Develop and maintain reusable R packages for data cleaning, transformation, and validation.
• Maintain complete, accurate, and audit-ready documentation and specs for all programming activities.

Required:

• Master’s or Bachelor’s degree in Data Science, Biostatistics, Computer Science, Life Sciences, or a related field
• Minimum 3 years Pharmaceutical/Biotech programming experience.
• Proficiency in R or Python, and experience with data visualization tools (e.g., Shiny, Spotfire, Tableau) and R packages
• Understanding of EDC and clinical trial processes
• Demonstrated ability to collaborate with cross-functional teams and translate non-technical requirements into technical…