Sr. Clinical Data Scientist

Overview

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. Summit believes in building a team of world class professionals who are passionate about this mission, and its people drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and a commitment to people.

Our employees are the heart and soul of our culture, invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

• Non-small Cell Lung Cancer (NSCLC) — HARMONi;
  Phase 3 evaluating ivonescimab with chemotherapy vs placebo plus chemotherapy in EGFR-mutated, locally advanced or metastatic non-squamous NSCLC previously treated with a 3rd generation EGFR TKI.
• HARMONi-3 — Phase 3 evaluating ivonescimab with chemotherapy vs pembrolizumab with chemotherapy in first-line metastatic NSCLC.
• HARMONi-7 — Phase 3 evaluating ivonescimab monotherapy vs pembrolizumab monotherapy in first-line metastatic NSCLC.

• Colorectal Cancer (CRC) — HARMONi-GI3:
  Phase 3 evaluating ivonescimab in combination with chemotherapy versus bevacizumab with chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

Summit is seeking a highly motivated Sr. Clinical Data Scientist to join our growing team. This role will be instrumental in advancing our technology-enabled and data-driven clinical data review and study monitoring strategy through automation, analytics, and cross-functional data support. The ideal candidate will be proficient in R and/or Python and apply these skills across clinical data domains to enhance processes, increase efficiency, and elevate data quality.

A strong focus on workflow optimization, coupled with a passion for implementing technical solutions in a fast-paced pharmaceutical environment, will be essential for success.

• Develop clinical study reports, dashboards, and data visualizations using R or Python.
• Partner closely with the Data Management team to implement data-monitoring or reconciliation listings and edit checks that support ongoing data review.
• Collaborate with Clinical Operations to generate study metrics and identify potential site-level risks.
• Communicate requirements clearly with vendors, author and curate specs, and ensure the results delivered by vendors.
• Perform data wrangling and data processing in R/Python to support the summarization and interpretation of clinical trial data.
• Build ETL pipelines in a Windows environment to automate clinical data workflows and streamline clinical programming activities.
• Develop and maintain reusable R packages for data cleaning, transformation, and validation.
• Maintain complete, accurate, and audit-ready documentation and specs for all programming activities.

Required

• Master’s or Bachelor’s degree in Data Science, Biostatistics, Computer Science, Life Sciences, or a related field
• Minimum 3 years Pharmaceutical/Biotech programming experience
• Proficiency in R or Python, and experience with data visualization tools (e.g., Shiny, Spotfire, Tableau) and R packages
• Understanding of EDC and clinical trial processes
• Demonstrated ability to collaborate with cross-functional teams and translate non-technical requirements into technical solutions
• Ability to work well under pressure and shift priorities, both as a team leader and as a team member
• Clear oral and written communication

• Experience with maintaining data visualization systems
• Experience with Github
• Prior experience in oncology or complex therapeutic areas
• Ability to proactively identify and address project uncertainties to minimize risk
• Strong problem solving and analytical skills

The pay range for this role is $148,000-$174,500 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at  to obtain prior written authorization before referring any candidates to Summit.