Senior Research Associate, Neuroscience

Senior Research Associate, Neuroscience

Gondola Bio is a clinical‑stage biopharmaceutical company focused on developing next‑generation therapeutics for genetic diseases. Originally launched as Bridge

BioX, a subsidiary of Bridge Bio, Gondola Bio secured $300M in private financing from external investors in 2024 and became an independent company within the Bridge Bio ecosystem. The company aims to leverage cutting‑edge biological research to create breakthrough medicines addressing high unmet needs across multiple therapeutic areas, including neurology, pulmonology, cardiology, nephrology, and endocrinology. Located on the Stanford Life Sciences campus, Gondola Bio fosters a unique hybrid environment where top scientists from around the world collaborate with senior leadership and advisors, blending industry expertise with academic innovation.

You are a technically strong and highly organized research associate with hands‑on expertise in stem cell culture and neuronal differentiation. You have direct experience culturing human iPSCs and differentiating them into neurons, and you understand the precision required to generate reproducible, screening‑ready cellular models.

You are comfortable operating in 96‑ and 384‑well formats, executing structured workflows, and generating high‑quality datasets to support discovery programs. You have experience in multiple biochemical and imaging assay formats and preferably have utilized multielectrode array technology. You take ownership of your work, maintain rigorous documentation, and thrive in a fast‑paced biotech environment. You communicate clearly, collaborate effectively across teams, and are energized by contributing to programs that aim to deliver transformative medicines to patients.

This role will support neuroscience‑focused discovery programs and contribute directly to in‑vitro screening of candidate therapeutics. This position requires a regular on‑site presence at our lab in Palo Alto, CA typically 5 days per week.

• Culture and maintain mammalian cell lines, primary cells, and human iPSCs
• Differentiate iPSCs into disease‑relevant neuronal subtypes and enhance workflow robustness and reproducibility
• Establish and manage cell banking processes, including QC, cryopreservation, and inventory tracking

• Design and execute cell‑based screening assays to deliver timely, high‑quality data
• Perform molecular and cellular readouts including viability, gene and protein expression (e.g. qPCR, Western blot), and phenotypic characterization (e.g. electrophysiology studies using the MEA platform)
• Optimize transfection conditions, dosing paradigms, and assay parameters to ensure reliable compound characterization
• Generate high‑quality, well‑controlled datasets to inform program decision‑making
• Integrate laboratory automation into experimental workflows

• Present data clearly in team meetings and contribute to written summaries and reports
• Collaborate closely with colleagues across discovery biology and chemistry teams to advance research objectives

• B.A. or B.S. in Neuroscience, Cell Biology, Molecular Biology, Biochemistry, or a related scientific discipline
• Minimum 2 years of industry experience in biotechnology or pharmaceutical research
• Hands‑on experience culturing human iPSCs and differentiating iPSCs into neuronal subtypes
• Experience maintaining multiple mammalian cell types under sterile technique
• Experience working in 96‑ and 384‑well plate formats
• Experience establishing and managing cell banks or cell repositories with strong organizational and quality control practices
• Strong understanding of assay controls, experimental design principles, and data quality standards
• Excellent organizational skills and attention to detail
• Strong written and verbal communication skills
• Ability to operate effectively in a fast‑paced, milestone‑driven discovery environment

• M.S. in a relevant scientific discipline
• Experience working with antisense oligonucleotides (ASOs), siRNA, or other oligonucleotide…