Director, Global Trade and Operations Strategy ; Verona,

Overview

Director, Global Trade and Operations Strategy

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics.

Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI.

Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Director, Head of Global Trade Operations and Strategy is a key Supply Chain leader responsible for designing, implementing, and overseeing Arrowhead’s global trade compliance program while shaping trade-related strategy to support the company’s continued growth, resilience, and innovation. This role ensures compliance with applicable international trade regulations while enabling efficient, ethical, and scalable global operations across R&D, manufacturing, clinical, and commercial activities.

This individual will set the direction for Arrowhead’s global trade policy, operating model, and strategy; drive proactive engagement with regulatory authorities; and partner closely with senior and executive leaders across Supply Chain, Commercial, Legal, Finance, Tax, Regulatory, and Quality to align trade compliance strategies with business objectives.

This position reports to the Vice President, Global Operations & Supply Chain. This role is based in Pasadena, California or Verona, WI with an expectation to be in the office five days a week.

Note:

Removed non-job content and applicant-facing elements to maintain focus on the role responsibilities and requirements.

• Global Footprint & Operating Model
• Design and evolve Arrowhead’s global trade and operating model, including importer-of-record/exporter-of-record structures, legal entity setup, intercompany flow design, and ex-U.S. supply pathways, to support commercial activation in new geographies.
• Lead country activation from a trade and Operations perspective, partnering with Regulatory, Commercial, Finance, Tax, and Legal to define the operating model, supply pathway, and trade documentation required to enter each market.
• Anticipate and enable footprint changes required as Arrowhead expands from rare disease into broader patient populations and grows its international commercial presence.
• Partner with Global Network & Risk to ensure the global operating model and physical supply network are aligned, complementary, and mutually enabling.
• Own and continuously enhance Arrowhead’s global trade compliance framework, including import/export policies, standards, and procedures aligned with U.S. CBP, OFAC, DEA, FDA, and relevant international agencies and programs, including those in the EU, UK, Japan, and other applicable markets.
• Maintain the governance model for global trade compliance, including oversight of risk assessments, monitoring activities, internal controls, and executive-level reporting.
• Ensure robust internal controls are in place across R&D, clinical, and commercial supply chains for classification, valuation, licensing, documentation, restricted party screening, sanctions…