Executive Director, Strategic Operations

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein.

Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics.

Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Executive Director, Strategic Operations is essential for steering Arrowhead’s strategic planning and operational excellence to ensure the seamless execution of our Global Operations and Product Delivery. As the Strategy and Operations Leader, you will play a vital role in facilitating the alignment and governance of Arrowhead’s technical portfolio, so we can achieve business agility. You will be responsible for the refinement and prioritization of our portfolio, developing our functional operating rhythm, and ensuring cross-functional alignment.

This role is based in Pasadena, California, with an expectation to be in office 5 days a week. This position is posted at the Executive Director level; however, depending on the selected candidate’s experience and qualifications, the role may be filled at the Senior Director level.

• Portfolio Management Facilitate the refinement and prioritization of the technical portfolio backlog, ensuring strategic alignment and optimal resource allocation. This role ensures our product and work package teams are in a constant state of readiness to anticipate and act on external changes.
• Operational Management Develop and manage functional operating rhythm to enhance organizational efficiency and effectiveness. Lead operational reviews and ensure execution against strategic plans.
• Long Range Planning Lead strategic planning for lifecycle management (LCM) across the Global Operations and Product Delivery portfolio with focus on maximizing the long-term value of our assets
• Trade Operations Oversee the global trade policy and strategy direction, drive proactive regulatory engagement, and partner with senior and executive leadership across Supply Chain, Commercial, Legal, Finance, Tax, Regulatory, and Quality to align trade compliance strategies with business growth.
• Functional Alignment Foster alignment and integration across teams ensuring proactive collaboration and cohesion in achieving strategic goals.
• Risk Management and Network Strategy Develop critical manufacturing strategies and plans identifying operational factors that impact capacity and network limits. Recommend strategies supporting business case development and investments
• Governance Process Play an integral role in the governance process for the technical portfolio, including partnerships and licensees requiring Arrowhead CMC or Supply services, ensuring that decisions are made transparently and effectively. The Governance team will understand the financial, technical, and business contexts & hold strategy and…