Senior Clinical Research Associate - CNS​/Cardiovascular

Piper Companies is seeking an experienced Senior Clinical Research Associate (CRA) to support CNS and Cardiovascular clinical studies in a dynamic, sponsor‑facing environment. This role will be responsible for overseeing site performance, ensuring regulatory compliance, and driving successful trial execution through strong site relationships and hands‑on monitoring activities. This is a full time opportunity that requires regional travel and can be located anywhere in the U.S.

• Independently monitoring Phase II–III CNS and Cardiovascular clinical trials to ensure compliance with study protocols, ICH‑GCP guidelines, and regulatory requirements.
• Conducting site initiation, routine monitoring, and closeout visits while maintaining high‑quality oversight of investigative sites.
• Performing source data review (SDR), source data verification (SDV), and case report form (CRF) review to ensure accurate and inspection‑ready study data.
• Building strong partnerships with investigative sites to support enrollment goals, protocol adherence, and overall study success.
• Collaborating directly with sponsors, study teams, and site personnel while providing regular updates on site performance and trial progress.

• 1+ years of Clinical Research Associate experience, including significant experience independently monitoring CNS and/or Cardiovascular clinical trials.
• Strong knowledge of ICH‑GCP guidelines, FDA regulations, clinical trial operations, and site management best practices.
• Experience supporting Phase II and Phase III studies with responsibility for site oversight, monitoring, and issue resolution.
• Proven ability to conduct site initiation, interim monitoring, and closeout visits independently.
• Strong sponsor‑facing communication skills and experience working directly with biotechnology or pharmaceutical clients.
• Ability to manage multiple investigative sites, prioritize competing demands, and work effectively with minimal supervision.
• Must be located within reasonable distance of a major airport and willing to travel regionally as required.

• Salary range: $100,000 - $115,000.
• Comprehensive benefits package including Medical, Dental, Vision, 401k, PTO, holidays, and sick leave as required by law.

This job is open for applications on 7/1/2026 and will remain open for at least 30 days from the posting date.